ACTIVITY 1: The Effect of Arteriole Radius on Glomerular Filtration Answers
1. According to your lab manual, in humans the glomerular filtration rate (GFR) ranges from _____ to _____ ml/minute. 80
2. When the radii of both the afferent arteriole and efferent arteriole were set at 0.45mm, the GFR was approximately ______ ml/minute.
d. 120 C.
3. True or False: Drinking a lot of caffeine (coffee or cola) leads to an increased urine volume. This might result from a decrease in the radius of the efferent arteriole. True
4. What are two primary functions of the kidney? Excretion-filters water and solutes in the blood, the kidneys are able to excrete excess water
Regulation- regulates plasma osmolarity which is the concentration of solution expressed as osmoles of solute per liter of solvent, plasma volume, body's acid-base balance, and body's electrolyte balance.
5. What are the components of the renal corpuscle? Bowman's capsule- renal corpuscle consist of a ball of capillaries called glomerulus and enclosed by a fluid-filled capsule called Bowman's capsule
Glomerular Capillaries- this is another name for the renal corpuscle. An afferent arteriole supplies the blood to the glomerulus. The blood flows through the glomerular capillaries, protein-free plasma filters into the Bowman's capsule, and known as the glomerular filtration. The afferent arteriole then drains glomerulus of the remaining blood.
6. Starting at the renal corpuscle, list the components of the renal tubule as they are encountered by filtrate. 1.Proximal convoluted tubule
2.Loop of Henle (U-shaped hairpin loop)
3.Distal convoluted tubule- before emptying into a collecting duct, from collecting duct, filtrate flows and collects in the minor calyces.
7. Describe the effect of decreasing the afferent arteriole radius on glomerular
References: Brandis K., (2001). Research for Question 22: Fluid Physiology and other Mechanisms of Water Balance. Retrieved from: http://www.anasthesiamcq.com/FluidBook/fl5_9.php Klabunde R. E., (1998-2010). Research on Question 22: Blood volume. Retrieved from: http://www.cvcphysiology.com/Blood%20Pressure/BP025.htm Chang 19 to False