Synthesis of Mdma

Topics: Sodium borohydride, Chemistry, Chemical reaction, Alcohol / Pages: 8 (1941 words) / Published: Jun 4th, 2007

All information here is to be used at your own risk. The procedures documented in this file, if carried out by unlicensed individuals would violate laws against controlled substances in most countries and could result in criminal charges being filed. If carried out by individuals unskilled at chemistry they could result in serious bodily harm.

MDMA ("Ecstasy") is a semi-synthetic compound which can be made relatively easily from available precursors. Synthesis instructions exist which can be followed by an amateur with very little knowledge of chemistry. However, people with less than 2 years of college chemistry experience would probably not be capable of sucessfully synthesizing MDMA, and would either botch it in the best case or kill themselves in the worst case. For those interested in the techniques involved in synthesizing MDMA, a good book for self- learning is the following:

Zubrick, James W. "The Organic Chem Lab Survival Manual: A Students Guide to Techniques." ISBN #0471575046. Wiley John&Sons Inc. 3rd ed.

It is recommended that this book should be supplemented with at *least* one more of the 'dry' and technical O-Chem lab manuals available at any college bookstore. It is not recommend that the information from these books or herein this file be used to synthesize MDMA for the previously stated reasons. Knowledge, however, is not (yet) illegal.


The following chemicals are some of the more important ones in the synthesis of MDMA and related chemicals:


safrole: 3,4-methylenedioxyallylbenzene, 1-(3,4-methylenedioxyphenyl)-2-propene

isosafrole: 3,4-methylenedioxypropenylbenzene, 1-(3,4-methylenedioxyphenyl)-1-propene

MDP-2-P: 3,4-methylenedioxyphenyl-2-propanone,
3,4-methylenedioxybenzyl methyl ketone, piperonylacetone piperonal: 3,4-methylenedioxybenzaldehyde, heliotropin

beta-nitroisosafrole: 3,4-methylenedioxyphenyl-2-nitropropene

References: ROAD HAZARDS: Chemical Abstracts 52, 11965c (1958): In the synthesis of MDA from MDP-2-P this reference has a misprint that should read "add 100ml H2O" instead of "add 100ml H2O2" which would cause an explosion

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