Topics: Asthma, Immune system, Mucus Pages: 2 (593 words) Published: November 1, 2014

Respiratory Drug Chart
DrugMechanismUseSide/Adverse EffectsNursing Implications
diphenhydramine hydrochloride-BENADRYL
ALLEGRA, CLARITIN, ZYRTEC -competes for H1 receptors -prevent & treat allergic responses -hypnotic—safe, non- narcotic
-anti-emetic Central nervous system side effect are: drowsiness, sedation, vertigo. Cardiovascular side effect are: hypotension, palpitations, arrhythmias Respiratory side effects are: dryness of mouth, thicken bronchial secretion Gastrointestinal : anorexia, diarrhea or constipation

Genitial urinary: urinary rentention, dysuraiAvoid pregnancy, and lactation Take anticholingeric caution with glaucoma, hyperthyroidism
Be caution about driving
Take meds at bedtime to avoid sedation
Bronchodilators Beta Agonists
Nonselective: Isoproterenol, Epinephrine, Ephedrine
Selective: albuterol, metaproterenol, terbutaline, salmeterol-stimulate beta-2 adrenoreceptors-bronchial smooth muscle relaxation -stimulate mucocillary clearance -“rescue therapy” during acute asthma attacks -prophylaxis for exercise- induced asthma

-prophylaxis for exposure to known antigens All nonselective effects: stimulation of cardiac beta Receptor such as tachycardia, arrhythmias and angina
Central nervous system: effects nervousness, anxiety, insomnia, dizziness and sweating It assess respiratory status It decrease environmental irrantantsNeeds to improve humidification Try to avoid OTC inhalers

Muscarinic-receptor antagonists (anticholinergics) -inhibits ACh mediated constriction of bronchial smooth muscle -decr. vagal-stimulated mucus secretion -treat chronic conditions; not for acute use Has systemic side effects minimal in cardiovascular Dryness of the oropharnyxMethylxanthines-inhibits phosphodiesterase leads to incr. cAMP so bronchodilation-decr. histamine release -stimulates ciliary transport of mucus

-improve contractility of diaphragm
-incr. CO, produces diuresis & decr. PV -prophylaxis &...
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