Cell Transport Mechanisms and Permeability
Activity 1: Simulating Dialysis (Simple Diffusion)
Describe two variables that affect the rate of diffusion: Two variables that affect the rate of diffusion are size and concentration gradient. The molecular size vs the MWCO size of the membrane can either increase, decrease, or prevent diffusion.
The greater the concentration gradient the greater the diffusion rate due to molecules moving from areas of higher concentration to areas of lower concentration.
Why do you think the urea was not able to diffuse through the 20 MWCO membrane? How well did the results compare with your prediction? My prediction was correct. The molecular weight of urea is 60.07 and is to great to pass through the 20MWCO membrane.
Describe the results of the attempts to diffuse glucose and albumin through the 200 MWCO membrane. How well did the results compare with your prediction? My prediction was correct in this experiment. Knowing that glucose is a monosaccharide, it is of size to diffuse through a 200MWCO membrane. Albumin being a protein is dense with 607 amino acids and an average molecular weight of 135g/mole is not going to diffuse through the 200MWCO membrane. During the experiment the left solute glucose at 9.00 passed through the 200MWCO membrane at a rate of 0.0042. The albumin did not diffuse through the membrane.
Put the following in order from smallest to largest molecular weight: glucose, sodium chloride, albumin, and urea: In order from smallest to largest is sodium chloride, urea, glucose, and largest albumin.
Activity 2: Simulated Facilitated Diffusion
Explain one way in which facilitated diffusion is the same as simple diffusion and one way in which it differs: Facilitated diffusion is the same as simple diffusion being that no energy is required for diffusion to take place. One way the two are different is that with facilitated diffusion a carrier protein is...
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