Cells: Structures & Processes
Organelles & Illness - Imagine that you are part of a research team that specializes in diagnosing disorders associated with malfunctioning cellular organelles and structures. Medical doctors consult you to provide a cellular explanation for particularly difficult cases. You recently received the two patient histories outlined below – what is your diagnosis? Note – this exercise is only asking you to determine which cell structure might be responsible for the condition.
Choose (1) Patient History to Diagnose
Patient 1: Seven-year old male exhibiting fatigue, muscle weakness, low endurance, loss of coordination, and progressive difficulty walking.
Physical Examination Results: Patient shows signs of muscle loss an deformity, an awkward gait, and difficulty breathing.
Laboratory Results: Patients cells are of an abnormal shape, cellular division is abnormal, and there is impaired intracellular (within the cell) movement of materials.
Patient 2: Two-day old male with low birth-weight (4lbs, 5oz), has difficulty suckling/swallowing, suffers from seizures and gastrointestinal bleeding.
Physical Examination Results: Enlarged liver, low muscle tone/inability to move, glaucoma, facial deformities, impaired hearing, and jaundiced skin.
Laboratory results: High levels of hydrogen peroxide in cells and high levels of fats and amino acids in cells.
Patient #: patient 1
Malfunctioning Organelle: mitochondria or cytoplasmic ground substance
Rationale for Diagnosis (explain how the patient information supports your diagnosis):
The symptom the patient exhibiting indicates that muscles and organs are not provided enough APT to well function. Besides, since patient cannot generate ATP, the cellular division also cannot work well. Because it this process also need ATP to provide energy.
Mapping Cell Respiration: Discuss the structure of the mitochondria with regard to the two major sets of reactions that