Aspirin and Its Therapeutic Uses

Topics: Aspirin, Myocardial infarction, Stroke Pages: 2 (530 words) Published: June 19, 2013
“Aspirin has been used for many years; it is well-understood, effective, inexpensive and widely available.” - Dr. Jeffrey Berger In the last 30 years medicines prescribed by doctors have changed beyond all recognition. Our better knowledge of the nature of diseases and their management has led to the replacement of many old remedies by new ones specifically designed for each illness. Everyone has known for years that aspirin is a fast and reliable painkiller that also reduces inflammation and cools fevers. More recently it has become just as well known as a help to people with heart complaints such as angina, coronary thrombosis and after coronary bypass surgery. It is becoming better known, too, in prevention of stroke. Among other diseases in which active research about aspirin is showing great promise - and in which it is now being increasingly used - are toxemia of pregnancy, diabetes, bowel cancer and dementia. How such an old drug can turn out to be so useful in so many crucial diseases makes a fascinating story. Astonishing advances in medical care need not depend entirely on the invention and introduction of new medicine! Aspirin, also known as acetylsalicylic acid, is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as and antipyretic to reduce fever, and as an anti-inflammatory medication. Aspirin was first isolated by Felix Hoffmann, a chemist with the German company Bayer in 1897. Acetylsalicylic acid (ASA) decomposes rapidly in solutions of ammonium acetate or of the acetates, carbonates, citrates or hydroxides of the alkali metals. ASA is stable in dry air, but gradually hydrolyses in contact with moisture to acetic and salicylic acids. In solution with alkalis, the hydrolysis proceeds rapidly and the clear solutions formed may consist entirely of acetate and salicylate. Aspirin is readily broken down in the body to salicylic acid, which...
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