In studies with mice, researchers have found certain molecules which could become the basis of new drugs. These drugs could change how chromatin functions to either turn on or off certain genes. In these experiments, small mice were forced to fight larger mice for a few days. They were kept in sight of each other but separated, and this caused the small mice to have a similar condition to depression in humans. By blocking the correct histones in the so called depressed mice, they had an antidepressant effect. This study shows that histones might be a possible target of new drugs. More tests need to be done before anything is for sure, but this is exciting stuff.
It opens up the possibility of a brand new type of antidepressant treatments, unlike anything we are using today. This could provide relief for patients who are not experiencing the desired results from current antidepressant medication and therapy. (10) As well as this, epigenetics could be the future of curing cancer. It could synergistically kill cancer cells by reactivating tumour-suppressor genes that had been turned off and re-sensitizing cells that are resistant to drugs. This would enhance the response to the more well known methods of killing off cancer, such as chemotherapy.