By: Nader Hossaini
George Mason University
Word count: 2281
Gonorrhea and its Causative Agent
Abstract
In this study, gonorrhea which is a sexually transmitted disease that can be found in every parts of the world including in the United States was investigated; gonorrhea passes from one person to another mainly through unprotected sexual activity. The causative agent for the disease, Neisseria gonorrhoeae, is a gram-negative coffee bean-shaped diplococci bacteria occurring in the form of two joined cells. The manner the bacteria initiate the disease is that Neisseria gonorrhoeae attaches to the epithelial cells which are …show more content…
Since gonorrhea is one of the common sexually transmitted diseases, getting it depends on the behavior of the individual at risk4. Therefore, the preventive majors for this disease are virtually identical to protecting against any other sexually transmitted illness. When it comes to the sexually transmitted disease of gonorrhea, it is clear that one should be tested for the disease as sometimes gonorrhea does not show any obvious symptoms. Especially women who are at risk should often check with a physician to make sure they are disease free. Screening programs are extremely helpful in identifying individuals that are infected with Neisseria …show more content…
The symptoms of severe gonorrhea are initiated by the irregular damage of the urethral mucosa with buildup of gonococci and polymorphs in the subepithelial connective tissues. During the three-to-five day asymptomatic interval that follows exposure, Neisseria gonorrhoeae seemingly become established on the urethral mucosa since they are not removed by frequent acts of micturition. An attachment of the gonococcus to the mucosal surface occurs before the invasion of deeper tissues while there is indication that the adhesion to epithelial cells is a factor that affects the distribution of bacteria in the mouth and gastrointestinal tract. Also, adherence to cells might be important in the pathogenesis of other mucosal infections. The best medication for this disease is the antibiotic penicillin; however, if the strains of Neisseria gonorrhoeae bacteria are resistant to penicillin, either a stronger dose of penicillin should be used or other types of strong antibiotics or an antibiotic mixture can be used that are proven effective against the causative agent of gonorrhea that are becoming more resisting to the antibiotic treatment, another antibiotic that is effective in treating gonorrhea is ceftriaxone3. Some strains of Neisseria gonorrhoeae have become very resistant to some antibiotics which indicate that