Endocrine System

Lab 1 – Exercise 4: Endocrine System

ACTIVITY 1: Metabolism and Thyroid Hormone

Part 1:

Chart 1: Effects of Hormones on Metabolic Rate

Normal Rat
Thyroidectomized Rat
Hypophysectomized Rat
Baseline
Weight
Ml O2 used in 1 minute
Ml O2 used per hour
Metabolic rate
Palpation results

250 grams 7.1 ml 426ml 1704 ml O2/kg/hr
NO MASS 245 grams 6.3 ml 378 ml 1542.86 ml O2/kg/hr
NO MASS 245 grams 6.3 ml 378 ml 1542.86 ml O2/kg/hr
NO MASS
With thyroxine
Weight
Ml O2 used in 1 minute
Ml O2 used per hour
Metabolic rate
Palpation results

250 grams 8.4 ml 504 ml 2016 ml O2/kg/hr
NO MASS 245 grams 7.8ml 468 ml 1910.20 ml O2/kg/hr 245 grams 7.8 ml 468 ml 1910.20 ml O2/kg/hr
With TSH
Weight
Ml O2 used in 1 minute
Ml O2 used per hour
Metabolic rate
Palpation results

250 grams 8.0 ml 480 ml
1920 ml O2/kg/hr
MASS

245 grams 6.4 ml 384 ml 1567.35 ml O2/kg/hr
NO MASS 245 grams 7.9 ml 474 ml 1934.69 ml O2/kg/hr
MASS
With propylthiouracil
Weight
Ml O2 used in 1 minute
Ml O2 used per hour
Metabolic rate
Palpation results

250 grams 6.3 ml 378 ml 1512 ml O2/kg/hr
MASS

245 grams 6.2 ml 372 ml 1518.37 ml O2/kg/hr
NO MASS 245 grams 6.3 ml 378 ml 1542.86 ml O2/kg/hr
NO MASS

1) Which rat had the fastest baseline metabolic rate? NORMAL RAT

2) Why did the metabolic rates differ between the normal rat and the