Epigenetics is the series of chemical modifications of DNA and its connected proteins that contain phenotypic information during cell division. These modifications alter gene expression without changing DNA sequence. They differ among tissues and change over throughout the organism’s lifetime. A well-understood example of epigenetic modification is DNA methylation‚ the process by which a methyl group is covalently bonded to cytosine. During DNA replication‚ a specific enzyme recognizes unmethylated
Premium DNA Gene Gene expression
Aspirin Synthesis Introduction Out of all the pharmaceutical drugs in the worlds‚ aspirin is made the most. Any potential pharmacist must be familiar with synthesizing the drug. The goal of this lab is to synthesize as much pure aspirin as possible. The reactants‚ acetyl anhydride and salicylic acid‚ must react in phosphoric acid. With phosphoric acid as a catalyst‚ the reaction yields aspirin and acetic acid. The equation for the reaction is as follows: “(CH3CO)2O + HOC6H4COOH □(→┴yields ) CH3CO2C6H4CO2H
Premium Stoichiometry Reagent Aspirin
use throughout the body. The liver is essential for monitoring and maintaining a relatively constant level of glucose in the bloodstream‚ hence the liver is involved in glycogen breakdown and synthesis because these pathways allow the liver to remove glucose from the bloodstream for glycogen synthesis when blood glucose is high and to release glucose into the bloodstream from glycogen breakdown when blood glucose levels are too low. Glycogen provides an additional source of glucose besides that
Premium Glycogen Glucose Metabolism
YOUR NOTES UNIT 2 NOTES DNA (deoxyribonucleic acid) DNA Functions • Stores genetic information and copies itself (replication) to pass on the information • Contains genes (instructions to make proteins) • Instructs cell’s activities DNA Structure • DNA is a polymer of nucleotides • Chromosomes (DNA strand + associated proteins ie. Histones wrap DNA around like a spool = condensed chromatin) ↓ genes (sections of a chromosome that codes for a protein) ↓ nucleotides (3 parts:
Free DNA
Effects of Differentiation on Enzymatic Activity Introduction HL-60 cells are capable of undergoing differentiation to induce different cell types. HL-60 cells can undergo morphological changes‚ changes in gene expression‚ and changes in protein synthesis. In the past weeks‚ we were able to conclude that HL-60 cells treated with DMSO and HL-60 cells treated with PMA will differentiate into granulocytes and monocytes upon treatment (1). We were also able to observe that both types of treated cells
Premium DNA Gene Gene expression
The structure and synthesis of TPC is outlined in Scheme 1. Briefly‚ the compound 1 was synthesized as per literature procedure. 2 was synthesized by reacting 1-methy pyrazole-4-boronic pinacol ester with 1 by suzuki-coupling‚ the final product TPC was synthesized by treating with malononitrile in the presence of piperidine as a base and ethanol as solvent. The detailed synthesis procedure given in the experimental section. The structure and purity of TPC was unambiguously confirmed by 1H and 13C
Premium Chemistry Acetic acid Alcohol
As shown in the balanced chemical reaction in figure 1‚ Felbinac is synthesized from 4-bromophenyl acetic acid‚ phenylboronic acid‚ and 10% Pd/C. Figure 1: The balanced chemical reaction showing the synthesis of felbinac. It functions by inhibiting cyclooxygenase-1‚ which releases prostaglandins that cause pain as a response to injury. In a study conducted by Moore et al.‚ 160 patients were subject to various topical NSAIDS to determine their effectiveness
Premium Oxygen Carbon Carbon dioxide
Racism has provoked inequality among Americans for centuries. Although it has been claimed to have dissolved‚ racism is still apparent in the very set up of our nation. It pulls apart the unity of our nation by forming groups that in time will break the equality and freedom given in America. The ideal of racism still exists in today’s society‚ having found new ways to insert itself into our everyday life. As segregation and slavery have faded from American culture it is socially accepted that‚ with
Premium Race Racism Black people
What does it really mean to be a man or a woman? Masculine or feminine? Different cultures and communities have assigned certain characteristics and attributes which define each sex. But do these traits describe every man and woman’s behavior? Individuals should have the free will to act in any way they wish to‚ whether in favor of society measures or in favor of their own conscience. Throughout the course of history‚ men have been viewed and perceived to be chivalrous‚ audacious‚ dauntless‚ and
Premium Gender Gender role Woman
Mechanism of chalcone formation Kinetic studies have been reported for the base-catalyzed formation of chalcone and its derivatives. [7‚ 8‚ 9] Two alternative mechanisms have been advanced for the reaction of benzaldehyde with acetophenone in the presence of a basic catalyst. 5 The formation of chalcone by the acid catalyzed condensation of acetophenone and benzaldehyde has been studied [10]. The following mechanism seems to be operating- 6 Importance of chalcones [1]They have close relationship
Premium Ultraviolet Hydrogen Catalysis