ERRORS IN MEASUREMENT Errors in Measurement Structure 2.1 Introduction Objectives 2.2 Classification of Errors 2.2.1 Gross Errors 2.2.2 Systematic Errors 2.2.3 Random Errors 2.3 Accuracy and Precision 2.4 Calibration of the Instrument 2.5 Analysis of the Errors 2.5.1 Error Analysis on Common Sense Basis 2.5.2 Statistical Analysis of Experimental Data 2.6 Summary 2.7 Key Words 2.8 Answers to SAQs 2.1 INTRODUCTION The
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to synthesise pure aspirin using chemical tests such as esterification and recrystallization independently and to also find out the melting point range of aspirin using melting point determination. INTRODUCTION Aspirin‚ which is also known as acetylsalicylic acid‚ is one of the commonly used and widely found in any drugstore or pharmacy. Its properties make aspirin a well-rounded drug that reduces inflammation and fever and also relieves pain. The active ingredient in aspirin was found to be salicylic
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History Of Aspirin Aspirin is one of the most commonly used drugs in the world.. For centuries people throughout the world. Aspirin was discovered about 3500 years ago. A collection of 877 medicinal recipes‚ The Ebers papyrus‚ before Christ‚ from the middle of the second millennium had been bought during the last century from an Egyptian street vendor by Georg Ebers‚ a German Egyptologist Georg. He recommended an infusion of dried myrtle leaves for rheumatic and back pain. More than a
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1. A physician forgets to tell a patient about the risk of combining a prescribed drug with aspirin and the patient takes two aspirin for a headache: In this scenario the extend of liability depends on the drug being prescribed‚ if the drug is dispensing in generic form with no warnings‚ then the physician could be considered liable‚ however it is still possible to make the argument that the patient would have been proactive about potential contraindications‚ and consult the dispensing pharmacy
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purity of my aspirin sample I produced. When I carried out the experiment to produce an aspirin sample I had to take a few results I had gained from carrying out the experiment later used these to work out the experimental error and percentage % yield. The results I used where the published value of what temperature pure aspirin melts at‚ the temperature my aspirin sample melted at‚ the weight of pure aspirin and the weight of impure aspirin. Firstly I worked out the experimental error by using this
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the University of Munich‚ isolated a tiny amount of bitter tasting yellow‚ needle-like crystals‚ which he called salicin (1828). Henri Leroux had improved the salicin extraction procedure to obtain about 30g from 1.5kg of bark (1829). An additional source of salicylic acid was found in 2835 by the German chemist Karl Jakob Lowig. This new wonder pain killer was found in Meadowsweet (Spiraea ulmaria)‚ a wild flowering plant that grows on riverbanks over much of Europe. Raffaele Piria [an Italian chemist]
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I. INTRODUCTION Synthesis Acetylsalicylic acid is an acetyl derivative of salicylic acid which appears as a white and crystalline and a weakly acidic substance with a melting point of 135°C and is also known to be aspirin. It is one of the most widely used drugs that can lower fever and is used as a painkiller. According to (Escobel‚ 2011)‚ Aspirin is synthesized through the reaction of salicylic acid with acetyl anhydride that causes a chemical reaction that turns salicylic acid’s hydroxyl group
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Investigating Aspirin Aims Synthesize my own aspirin Analyse the purity of my aspirin samples (aspirin and recrystallized aspirin) compared to commercial aspirin by use of analysing melting points‚ TLC plates and colorimetry tests Investigate how pH effects the rate of hydrolysis of aspirin Background theory Making my own sample of Salicylic acid (to then be converted into Aspirin) Salicylic acid (2-Hydroxybenzoic acid) can be made by hydrolysing methyl 2-hydroxybenzoate. Oil
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Today‚ aspirin is one of the most widely used medication on this Earth and has been since its popular breakout in the late 1890s. Long before we were born there was no such thing of a medication called aspirin. Instead‚ ancient people used willow leaves and bark from trees to help relieve oneself from pain and fevers. Aspirin as we come to know it in the form of an acetylsalicylic acid‚ was introduced to the world by Chemist Felix Hoffmann who was working at Bayer pharmaceutical company located in
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Aspirin Aspirin is a salicylate‚ also known as a non steroidal anti-inflammatory drug (NSAID). It is the generic name of acetylsalicylic acid and is used clinically to treat fever‚ pain and inflammation as it works by preventing the formation of prostaglandin. Prostaglandin is the active agent that is responsible for the sensitisation at the nerve endings. It can be administered orally‚ rectally or by intravenous route. (6) Benzene ring Carboxylic acid Ester Alkane Aspirin has a pKa of 3.49
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