Bovine Spongiform Encephalopathy Tyrosine - Chemical Properties: Aromatic -Toxicity: when given to mice intraperitoneally‚ at doses >1450mg/kg‚ Tyrosine is said to be toxic. In humans‚ prolonged exposure to Tyrosine could cause urinary system‚ blood and behavior problems.Prolonged skin exposure could cause dermatitis. National Fire Protection rates health hazard of Tyrosine a 1. -Flammability: May be combustible at high temperatures. No available flammability limits‚ but the flash
Premium Protein folding Prion Protein
Bovine Spongiform Encephalopathy Bovine spongiform encephalopathy (BSE) is a relatively new disease found primarily in cattle. This disease of the bovine breed was first seen in the United Kingdom in November 1986 by histopathological examination of affected brains (Kimberlin‚ 1993) . From the first discovery in 1986 to 1990 this disease developed into a large-scale epidemic in most of the United Kingdom‚ with very serious economic consequences (Moore‚ 1996). BSE primarily occurs in
Premium Cattle Bovine spongiform encephalopathy Infectious disease
brain tissue. Another way an individual can acquire the disease is through contact with opened sores or wounds present. Kuru can be considered a prion disease due to the fact it is part of a class of infectious diseases known as transmissible spongiform encephalopathies(TSE). One major difficulty associated with Kuru is that it has a long incubation period. That is‚ a person who has developed this disease will not show any symptoms for years‚ sometimes even decades. Some of the first symptoms an
Premium Transmissible spongiform encephalopathy Disease Infectious disease
Neurodegenerative Disorders: Alzheimer’s Disease 1. Amyloid Precursor Protein (APP) Alzheimer’s disease (AD) remains a major cause of senile dementia‚ which is characterised by an impairment of neuronal and synaptic function in addition to the accumulation of β-amyloid plaque and formation of neurofibrillary tangles within distinct portions of the brain (De Strooper and Annaert‚ 2000). Progression of this distinct pathology of neurodegeneration does not typically vary from patient to patient
Premium Transmissible spongiform encephalopathy Alzheimer's disease Prion
infectious or transmissible. In 1962 Gadjusek and Alepers began working together to try and determine the cause of this new brain disease. William Hadlow‚ a veterinarian neuropathologist‚ had been working on a disease called Scrapie when he learned about Gajdusek’s findings of Kuru. Hadlow then informed Gadjusek of his idea that Scrapie and Kuru seemed extremely similar to each other. Both Scrapie and Kuru resembled a spongiform defect on the brain tissue. Scrapie is a transmissible
Premium Brain Transmissible spongiform encephalopathy Cannibalism
Presentation Summary Fatal Familial insomnia (FFI) What is Fatal Familial Insomnia? Also known as FFI. Fatal Familial Insomnia (FFI) is a genetic sleep disorder - but it is a rare one. It has been diagnosed in less than 40 families worldwide‚ including the Chicago music teacher‚ Michael Corke‚ who featured in the BBC documentary The Man Who Never Slept. FFI begins as an unexplained sleeplessness during middle age and rapidly develops into a fatal insomnia. It is caused by a genetic mutation
Premium Sleep disorder Sleep deprivation Transmissible spongiform encephalopathy
for 14+ months. The patient eventually falls into a coma and tragically dies. Luckily‚ the ultimate chances for humans to acquire Mad Cow Disease are very‚ very low. In fact‚ there have only been 3 reported cases in the U.S.! “BSE (Bovine Spongiform Encephalopathy).” www.cdc.gov. CDC‚ 17/3/11. Web. 6/3/12 <www.cdc.gov/ncidod/dwrd/bse> “BSE and vCJD.” www.google.com. Google‚ 1/1/97-12. Web. 11/3/12 <www.google.com/search?tbm=isch&hl=en&source=hp&biw=1085&bih=814
Premium Bovine spongiform encephalopathy Transmissible spongiform encephalopathy Prion
References: CDC - Bovine Spongiform Encephalopathy (BSE). (n.d.). Centers for Disease Control and Prevention. Retrieved May 9‚ 2013‚ from http://www.cdc.gov/ncidod/dvrd/bse/ CDC - Prion Diseases. (2010‚ January 1). Centers for Disease Control and Prevention. Retrieved May 9‚ 2013‚ from http://www
Premium Prion Bovine spongiform encephalopathy Transmissible spongiform encephalopathy
Jordan Haenel 10/12/15 Review: Genetic susceptibility‚ evolution and the kuru epidemic. Simon Mead1‚ Jerome Whitfield1‚2‚3‚ Mark Poulter1‚ Paresh Shah1‚ James Uphill1‚ Jonathan Beck1‚ Tracy Campbell1‚ Huda Al-Dujaily1‚ Holger Hummerich1‚ Michael P. Alpers 1‚2‚3 and John Collinge1‚ The most well documented case of human prion disease epidemic occurred in the early to mid-twentieth century in the isolated Eastern Highland region of Papua New Guinea. The Fore group was specifically affected as
Premium Population genetics Prion Transmissible spongiform encephalopathy
commonly known as transmissible spongiform encephalopathies to date is untreatable and fatal. Some of the common prion disease found in humans includes Creutzfeldt-Jakob disease (CJD)‚ Variant Creutzfeldt-Jakob disease (vCJD)‚ Gerstmann-Straussler-Scheinker Syndrome‚ Fatal Familial insomnia‚ and Kuru. Besides human prions disease is also prevalent in animals causing Bovine Spongiform Encephalopathy (BSC) also known as mad cow disease‚ Chronic Wasting Disease‚ Scrapie‚ Transmissible mink encephalophathy
Premium Prion Immune system Bovine spongiform encephalopathy