Thalidomide was originally invented in the 1950s by the Swiss pharmaceutical company. It was then initially released by the German company Chemie Grunenthalas in 1957 and was advertised to be one of the safest sedative drugs which is non-addictive (Kim & Scialli‚ 2011). Additionally‚ due to its effect in helping pregnant women to reduce the symptoms of morning sickness‚ thalidomide became widespread around the world; it was sold in more than 40 countries and was known as different names; for example
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Thalidomide was developed by a German firm called Chemie Grunenthal. It was first developed as an anticonvulsant drug. Through early trials they discovered it would not be suitable for this purpose. The drug thalidomide became widely prescribed in the 1960’s and was mainly prescribed to pregnant women for morning sickness. Thalidomide beforehand had however been prescribed as an antidepressant‚ it was thought to be effective for both morning sickness and depression. After a short time it became obvious
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Thalidomide As you know a good number of drugs are chemical substances used in the treatment‚ cure‚ prevention‚ or diagnosis of disease or used to otherwise enhance physical or mental well-being. What most people don’t know is that some of them have side effect that could sometimes be deadly. Thalidomide is one of these drugs which caused “The biggest tragedy in medical history” in the modern time. Thalidomide was used as sedative prescribed to pregnant women to alleviate the symptoms associated
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in the treatment of cancer/ hematological malignancies through innovative drug development strategies have witnessed favorable outcomes. Over the past decade‚ Proteasome inhibitor‚ Velcade (bortezomib) and the immunomodulatory drugs – Thalomid (thalidomide) and Revlimid (lenalidomide) have become the cornerstone of treatment for patients with Multiple Myeloma (MM) resulting in improved survival. However‚ eventually all patients relapse and new treatment options for Relapsed/ Refractory Multiple Myeloma
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In the 1960s the drug thalidomide was used by some pregnant women in Europe and Canada to treat morning sickness. Women who took the drug in early pregnancy gave birth to children with severe birth defects such as missing or shortened limbs. More than 10‚000 children around the world were born with major malformations‚ many missing arms and legs‚ because their mothers had taken the drug during early pregnancy. Mothers who had taken the drug when arms and legs were beginning to form had babies with
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Thalidomide was a pharmaceutical produced by the German company Chemie Grünenthal that hit the market in 1957. It was intended for use as a sedative and treating morning sickness in pregnant women‚ along with a slew of other uses. Thalidomide was a miracle drug. It was much cheaper than many other sedatives‚ so many people could afford it. Due to the variety of uses‚ it could beneficial to almost everyone. It was advertised as so safe‚ even pregnant women could take it. Thalidomide was quickly made
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pharmaceutical company Chemie Grunethal discovered Thalidomide (alpha-phthalimido-glutarimide) whilst trying to create an effective anticonvulsant. After testing thalidomide on laboratory animals‚ Thalidomide was marketed as a sedative in 1956. Further research was done on Thalidomide at Chemie Grunethal‚ and‚ during this new round of research‚ it was found that the drug inhibited morning sickness. By 1957 the company was aggressively marketing Thalidomide as a panacea for morning sickness under the trade
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Kelsey and Thalidomide "If they are serious about admitting they are at fault and regret what happened‚ they need to start helping those of us who were affected financially." This quote was from Freddie Astbury‚ a victim of the side effects from the drug Thalidomide. Thalidomide was a drug that pregnant woman took in the 1960’s for morning sickness. Dr. Frances Kelsey‚ a medical officer for the FDA in 1960s‚ saved millions of babies from birth defects by calling attention to Thalidomide and single-handedly
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of medical drugs.Most pupils should be able to explain why drugs need to be tested before they can be prescribed. Describe the uses and problems associated with thalidomide.Some pupils will be able to explain how the drug testing procedure for thalidomide was inappropriate and describe the main steps in testing a new drug.Explain the terms placebo and double-blind trial.Ideas:Testing of new drugs and clinical trials. Thalidomide.Misconceptions: |
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Thalidomide Aim To appreciate that poor science can be harmful to people. Read the passages on thalidomide from the Internet and answer the questions that follow. 1 Thalidomide is a drug which was sold during the 1950s[->0] and 1960s[->1] as a sleeping aid and given to pregnant women to combat morning sickness[->2] and other symptoms. It was made in West Germany[->3] in 1953[->4]. It was available in around 50 countries‚ although not in the United States[->5]‚ under at least 40 different names
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