Experiment 29 – Borohydride Reduction of Vanillin to Vanillyl Alcohol Goal To perform a sodium borohydride reduction of an aldehyde to produce an alcohol. Reading and Working Ahead Your discussion should include a mechanism for this reaction. Review: OP 12 – Vacuum filtration OP 28 – Melting point (using Mel-Temp®) Procedure Notes Calculate the necessary mass of vanillin and sodium borohydride for the procedure below. Also calculate theoretical yield of vanillyl alcohol. You
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experiment of making borneol from camphor (FIGURE-3) is performed in two different methods‚ Sodium Borohydride Reduction and Meerwein-Ponndorf-Verley Reduction‚ to compare the relative product ratio of borneol to isoborneol. The concept of reduction and also oxidation‚ the opposite procedure of reduction‚ deals mostly with electron transfer between atoms. It will not be elaborated here‚ but the reduction procedure involved in this experiment is basically adding hydrogens and losing the carbon-oxygen
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Sodium borohydride Reduction of Benzil Introduction: The Purpose of this experiment is for the students to learn how to use sodium borohydride to reduce benzil to its secondary alcohol product via reduction reaction. This two-step reaction reduces aldehydes by hydrides to primary alcohols‚ and ketones to secondary alcohols. In order for the reaction to occur and to better control the stereochemistry and yield of the product‚ the metal hydride nucleophile of the reducing agents such as LiH‚ LiAlH4
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Experiment 5B: Ketone Reduction Objective: Using sodium borohydride as a reducing agent‚ the ketone 4-tert-butylcyclohexane is reduced to its corresponding alcohol. It is purified through extraction techniques to give the cis and trans diasteromer products. Procedure: The procedure was followed as outlined in Mayo’s book for Experiment 5B with the following modifications: 1. Reagents and Equipment – The reaction will be on a scale of 2X what is described in the text. 2. Reagents and Equipment
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John Heger CMY 211 Lab Section 13 11-30-2011 Borohydride Reduction of Vanillin to Vanillyl Alcohol Introduction: The purpose of this lab was to reduce vanillin to vanillyl alcohol. This lab report recaps the procedure and results of the lab. The chemical process studied in this lab was reduction‚ the process of reducing the number of bonds to oxygen and increasing the number of bonds to hydrogen. Other chemical processes included in the lab were recrystallization‚ melting point‚ and extraction
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Entwistle‚ Maria Amos‚ and Paul Golubic CHEM 0330 Organic Lab 1 Sodium Borohydride Reduction: Diphenylmethanol from Benzophenone 11/16/11 Introduction Redox (shorthand for REDuction-OXidation) reactions are chemical reactions in which the oxidation state (or oxidation number) of atoms has changed. Oxidation can be observed through the loss of electrons or an increase in oxidation state by an atom‚ ion or molecule. Reduction describes the gain of electrons or decrease in oxidation state of
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Lab 12: Reduction of an Aldehyde to a Primary Alcohol by Use of NaBH4Purpose(i)To select an appropriate solvent system. (ii)To synthesize alcohol from aldehyde by NaBH4 reduction. (iii)To identify the aldehyde isomer based on the melting point of the alcohol produced. Procedure(Please refer to the detailed instructions on lab 12 handout)Physical Quantity TableType of substanceMolecular FormulaMolecular Weight (g/mol)Density(g/cm3)Melting Point(oC)Boiling Point(oC)HazardO-vanillinC8H8O3152.15-42
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INTRODUCTION: All information here is to be used at your own risk. The procedures documented in this file‚ if carried out by unlicensed individuals would violate laws against controlled substances in most countries and could result in criminal charges being filed. If carried out by individuals unskilled at chemistry they could result in serious bodily harm. MDMA ("Ecstasy") is a semi-synthetic compound which can be made relatively easily from available precursors. Synthesis instructions exist which
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Borohydride Reduction of a Ketone Results 1. Draw a three-dimensional structure of the stereoisomer formed in the reaction. Name the compound. meso-Hydrobenzoin 2. Include other results as suggested by your data. * The attached IR and NMR spectroscopy data. * The melting point that ranges from 135.6-137.90C. Spectroscopic Analyses Data tables IR Spectroscopy Hydrobenzoin Peaks (cm-1) | Stretches | Intensity | 3332 (cm-1) | O—H stretch | Strong and broad | 3027
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SODIUM gSodium is a chemical element with the symbol Na (from Latin: natrium) and atomic number 11. It is a soft‚ silver-white‚ highly reactive metal and is a member of the alkali metals; its only stable isotope is 23Na. The free metal does not occur in nature‚ but instead must be prepared from its compounds; it was first isolated by Humphry Davy in 1807 by the electrolysis of sodium hydroxide. Sodium is the sixth most abundant element in the Earth’s crust‚ and exists in numerous minerals such
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