09/08/2012 Sickle Cell Disease Blood has been considered the essence of life for centuries‚ and our blood is a living tissue made up of liquid and solids. There are many diseases related to blood such as anemia which is the decrease in oxygen supply to tissue and causes hypoxia‚ thalassemia is the mutation in one or more globin gene of hemoglobin‚ etc. Therefore‚ one of blood disorders is the most common symptomatic hemoglobinopathy with the greatest prevalence in worldwide which is called sickle cell
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Sickle Cell Disease Physical-Adult • Eye problems. The retina‚ the "film" at the back of the eye that receives and processes visual images‚ can deteriorate when it does not get enough nourishment from circulating red blood cells. Damage to the retina can be serious enough to cause blindness. • Jaundice‚ or yellowing of the skin‚ eyes‚ and mouth. Yellowing of skin and eyes. These are signs of jaundice‚ resulting from rapid breakdown of red blood cells. • Delayed growth and puberty in children
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TREATMENT OPTIONS There is NO cure for sickle cell disease‚ although new stem cell research is promising. Bone marrow transplant is a potential cure‚ however finding a matched sibling donor is difficult. Therefore treatment is primarily focused on management of symptoms and prevention of pain episodes. Hydroxyurea (a chemotherapeutic medication) is the only recognized treatment option for the prevention of vaso-occlusive crisis in SCD. It is a prescribed drug for adult patients
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‘How could natural selection increase the number of children born with sickle-cell disease in certain regions when these individuals are unlikely to survive and produce offspring?’ Darwin’s theory proposes that 3 conditions are a requisite for natural selection to occur. They are a struggle for existence of the offspring as they are competing for limited resources‚ variation within species which gives some individuals advantage over others hence better chance of survival and lastly inheritance
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Genetics- Word Count: 214 Sickle cell disease is a genetic blood disorder that plagues millions of people all over the world‚ the highest concentration is found among people of Sub-Saharan African descent. Sickle cell disease is caused by a mutation in the HBB gene located on chromosome 11. Hemoglobin in red blood cells is how oxygen is delivered to cells throughout the body and is composed of four subunits‚ two subunits of alpha- globin and two of beta- globin. The HBB gene provides the instructions
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Sickle-Cell Disease Greatly affecting the body’s oxygen levels due to mutated red blood cells‚ sickle-cell disease‚ influences an individual’s childhood in multiple ways: cognitive‚ social‚ emotional‚ and physical development. Sickle-cell disease (SCD) refers to an inherited disorder where abnormal hemoglobin is present in one’s red blood cells. Hemoglobin is the protein in red blood cells responsible for carrying oxygen throughout the body. The deformed sickle hemoglobin in people with SCD can form
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Sickle Cell is an inherited blood disorder that affects approximately 100‚000 people in the United States. Red blood cells contain hemoglobin which is a protein that carries oxygen through the blood. Normal red blood cells are flexible and round. This allows them to travel through the small blood vessels and deliver oxygen to all of the body. Sickle cell disease(SCD) causes these red blood cells to form into a crescent shape‚ like a sickle. The sickle-shaped red blood cells easily break apart‚ causing
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Cell’s July 18‚ 2011 Sickle cell anemia is an inherited blood disease that means you are born with it and it lasts a lifetime. People with sickle cell anemia inherit two variant or sickle cell genes‚ one from each parent. In the United States‚ sickle cell anemia affects about 72‚000 people. About 2 million Americans carry the sickle cell trait but about 1 in 12 African Americans have the trait. The signs and symptoms of sickle cell anemia are different in each person. Some people
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Evolution of Disease Sickle Cell Anemia Sickle Cell Anemia is a disease that which the red blood cells form an abnormal sickle or crescents shape. Red blood cells are very important to the human body because they carry oxygen throughout the body. The main causes of Sickle cell is when the cells in the body mutate into abnormal cell called haemoglobin S. Haemoglobin S causes the red blood cells to become sickle shaped‚ rigid. This causes to make it more difficult for the cells to flow the vein
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Sickle cell disease (SCD) is a group of inherited conditions that affect the red blood cells. People affected with sickle cell disease produce abnormally shaped red blood cells that causes health problems. Sickle cell disease is caused by a defective gene passed on from the parent to the child. Sickle cell disease is condition that is considered serious and lifelong. People of African descent are mainly affected with sickle cell disease in addition to ‚ Caribbean‚ Middle Eastern‚ Eastern Mediterranean
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