Adams 1 Dwayne Adams Instructor: Croshaw Medical Terminology 1 18‚ April 2013 Sickle Cell Anemia Sickle-cell Anemia is a genetic blood disorder caused by the presence of an abnormal form of hemoglobin molecules in which the red blood cells loose their disc-shape and become crescent shaped. The shape also known as “hemoglobin S”. unlike normal red cells which are usually smooth and malleable‚ tend to collect after releasing oxygen‚ and cannot squeeze through small blood vessels. The
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Sickle cell anemia is a genetic disease that affects the shape and functionality of red blood cells. It is caused by a mutation in the DNA of the protein‚ hemoglobin‚ specifically in the beta chain. There are 531 base pairs in this DNA strand. Substitution or point mutation occurs‚ causing “GAG” to become “GTG”. This results in valine being created instead of glutamate. The mutation causes the hemoglobin to cling together in low oxygen levels and the red blood cell changes shape‚ preventing it from
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Cell’s July 18‚ 2011 Sickle cell anemia is an inherited blood disease that means you are born with it and it lasts a lifetime. People with sickle cell anemia inherit two variant or sickle cell genes‚ one from each parent. In the United States‚ sickle cell anemia affects about 72‚000 people. About 2 million Americans carry the sickle cell trait but about 1 in 12 African Americans have the trait. The signs and symptoms of sickle cell anemia are different in each person. Some people
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Critical Care Nursing: Sickle Cell Anemia Critical Care Nursing 10/15/2009 Sickle cell anemia affects millions of people worldwide. Sickle cell anemia is a disease in which your body produces abnormally shaped red blood cells. They don’t last as long as normal‚ round red blood cells‚ which leads to anemia. Sickle cells contain abnormal hemoglobin that causes the cells to have a sickle shape. Sickle-shaped cells don’t move easily through your blood vessels. They’re
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Sickle Cell Anemia is a hereditary disease that changes the smallest and most important components of the body. A gene causes the bone marrow in the body to make sickled shapes‚ when this happens; it causes the red blood cell to die faster. This is what causes Hemolytic Anemia. Older children and adults with sickle cell disease may experience a few complications‚ or have a pattern of ongoing problems that shorten their lives. The most common and serious complications of sickle cell disease are anemia
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Evolution of Sickle Cell Sickle Cell was discovered in the United states although it originated in Africa . The sickle cell disease (SCD) describes traits of an inherited red blood cell disorder‚ having SCD means you have abnormal hemoglobin‚ called hemoglobin S or sickle hemoglobin‚ in your red blood cells. What is hemoglobin u might ask?! Well Hemoglobin is a protein in red blood cells that is suppose to carry oxygen throughout the body. But when a sickle cell trait is “Inherited” it could
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SCD also known as sickle cell disease affects the blood and cardiovascular system. There are six different types of SCD. The following discussion will include cause‚ symptoms‚ diagnosis‚ treatment and prevention. The proper education on this disease will give patients and the public a better knowledge of the common unfamiliarity with SCD. The cardiovascular system consists of the heart‚ arteries‚ capillaries‚ veins‚ and blood. The organs in the cardiovascular system are a vital part of the human
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Sickle-Cell Anemia is a genetic blood disorder caused by the presence of an abnormal form of hemoglobin. These hemoglobin molecules tend to aggregate after unloading oxygen forming long‚ rod-like structures that force the red cells to assume a sickle shape. Unlike normal red cells‚ which are usually smooth and malleable‚ the sickle red cells cannot squeeze through small blood vessels. When the sickle cells block small blood vessels‚ the organs are deprived of blood and oxygen. This leads to periodic
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09/08/2012 Sickle Cell Disease Blood has been considered the essence of life for centuries‚ and our blood is a living tissue made up of liquid and solids. There are many diseases related to blood such as anemia which is the decrease in oxygen supply to tissue and causes hypoxia‚ thalassemia is the mutation in one or more globin gene of hemoglobin‚ etc. Therefore‚ one of blood disorders is the most common symptomatic hemoglobinopathy with the greatest prevalence in worldwide which is called sickle cell
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risking him or her having Sickle Cell Disease. What this is is it’s a disease that is genetically inherited and it involves the red blood cells. Mutations in the HBB gene cause this disease. This disease is inherited in an autosomal recessive pattern‚ which means both copies of the gene in each cell will have mutations. The parents of offspring with an autosomal recessive gene each carry one copy of the mutated gene. The blood cells form an abnormal crescent shape (normal cells are in a disk form)
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