Benzoate from Benzoic Acid October 28‚ 2010 Abstract: This experiment was conducted to synthesize methyl benzoate from benzoic acid and methanol by using the Fischer esterification method. Methanol (12.5ml) and Benzoic acid (4.9 grams) are heated together in the presence of concentrated sulfuric acid (1.5ml) until equilibrium is achieved. A reflux apparatus is set up for 1 hour to carry out the reaction at the boiling point of the solvent (Methanol‚ 2.5ml). Then‚ separation though an extraction
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TWO-BASE EXTRACTION OF BENZOIC ACID‚ 2-NAPHTHOL‚ AND NAPHTHALENE FROM UNKNOWN SAMPLE # 131 Douglas G. Balmer (T.A. Mike Hall) Dr. Dailey Submitted 11 July 2007 Introduction: The purpose of this experiment was to separate a sample of benzoic acid‚ 2- naphthol‚ and naphthalene of unknown proportions using a two-base extraction method. The three components of the mixture will react differently to sodium bicarbonate and sodium hydroxide because each of the bases’ conjugate acids has a different pKa
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Acid-Base Extraction: Separation of an Organic Acid‚ Base and a Neural Compound Introduction/Background Acid base extraction is a widely used commercial method in separating acids‚ bases and neutral compounds. This is concept is based on several physical properties of the compounds‚ such as boiling point‚ melting points and solubility. The different solubility properties of the protonated and non-protonated forms of these compounds depend on the functional groups present‚ such
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Experiment 2&3 Recrystallization and Melting Points Determinantion of Benzoic Acid Abstract In experiment 2‚ recrystallization was used to purify the crude benzoic acid extracted from a mixture during experiment 1. Then a percent recovery for this recrystallization process was calculated. In experiment 3‚ the melting point ranges of the crude and purified benzoic acid were both determined by using Melt Temp Apparatus. Introduction Recrystallization is a purification technique for non-volatile
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Extraction of R’-NH2 For both of the organic acid and organic base extraction‚ the addition of the respective inorganic acid or inorganic base (HCl or NaOH) to the three-component mixture caused an immiscible appearance of the solution in the separatory funnel. By briskly shaking the separatory funnel with the mixed components created a build up of pressure which was released through the stopcock forming small disappearing bubbles within the tip of the separatory funnel. Once the funnel was placed
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De-esterification for Synthesis of Benzoic Acid BATCH REACTOR Shane Bulk Chris Crosley David McGuire Max Skula Yunjing Song Shriram Sundarraj Nelson Zhou 155:416 Process Laboratory II Professor Jerry Sheinbeim January 28 – February 28‚ 2014 ABSTRACT The observed reaction that took place in this experiment was the de-esterification of ethyl benzoate to form benzoic acid. This experiment was used to determine the rate constant k of the synthesis of benzoic acid at different temperatures
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BROMINATION OF ACETANILIDE OBJECTIVE Aim of the experiment was too brominate acetaldehyde to form p-bromoacetanilide. INTRODUCTION Acetanilide is a chemical compound with the chemical formula of C6H5NH(COCH3). It is a crystalline solid that is prepared by acetylation of analine and is widely used in the dye industry. This crystalline solid is an odourless solid chemical that has a flake or leaf like appearance. It is also known as N phenylacetamide‚ acetanil or acetanilide. Its former
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Bromination of Acetanilide Objective: The objective of this experiment was to use melting point and NMR to determine which of two isomers‚ ortho or para‚ would most likely form after brominating Acetanilide through electrophilic aromatic substitution. Procedure/Observations: 1. Weigh out ~280 mg of acetanilide in a 10 mL r.b. flask with a stir bar. 2. Then‚ add 2.0 mL of glacial acetic acid using a calibrated Pasteur pipet. 3. Stir the mixture until all of the acetanilide has dissolved
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Synthesis of Acetanilide By: Rick Whitely April 9‚ 2013 Organic Chemistry Lab 1; Professor J. Hutchison Recrystallization is a common method of purifying organic substances through the differences in solubility at different temperature. In this experiment‚ acetanilide was produced by acetylation of aniline with acetic anhydride. The crude acetanilide was dissolved in a solvent in a heated water bath. The solution was cooled slowly in an ice bath as crystals form out. As the compound crystallizes
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Synthesis of Acetanilide Reaction O NH2 + H3C C O O C CH3 O N C CH3 H + H3C O C OH Aniline Acetic anhydride Acetanilide Acetic acid Purpose: Acetanilide is a useful precursor to many pharmaceuticals such as acetaminophen and penicillin. Experimental Procedure. (Estimated time: 1.5 h.) Unless otherwise noted‚ all manipulations should be done in the chemical fume hood. Place 100 µL of aniline into a tared 10 X 75-mm test tube (standing in a small beaker or Erlenmeyer flask). Now add
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