November 2011 Scleroderma My interest in Scleroderma is based upon personal experience and my own need to be further educated. I first heard of the disease when my older sister Meredith “Duffy” became afflicted with it. She contracted it after her treatment of Acute Myeloid Leukemia (AML). The treatment of AML and the stem cell transplant she received caused her to have GVHD (Graft Versus Host Disease). GVHD is a complication that can occur after a transplant in which the newly transplanted
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for in my relatively short existence on this earth I have watched my aunt battle a disease which literally changed every aspect of her life and day to day living. Scleroderma is a chronic auto-immune disease of the connective tissue. Coming from two Greek words ‘sclera’ and ‘derma’ which mean ‘hard’ and ‘skin’ respectively‚ scleroderma in actuality is the hardening of the skin. One can therefore just imagine the devastating effects that this can have on the body given that the skin is the largest
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Scleroderma There is a skin disease known as scleroderma that is defined as a chronic connective tissue disorder. Scleroderma is when there is an overproduction of collagen fiber‚ which causes sclerosis (hardening) and fibrosis (scarring) in the skin. Collagen fibers are a type of protein that have great strength and flexibility for certain structures of the body. They are one of the biggest components that make up the connective tissue‚ which is why this disease is known as a connective tissue
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specific complications‚ such as proton pump inhibitors and pro-kinetic agents for gastrointestinal problems‚ or light treatments for skin thickening. References. http://www.sclero.org/medical/about-sd/a-to-z.html#sd http://www.patient.co.uk/health/Scleroderma-Systemic-Sclerosis.htm http://www.sclero.org/
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The patient showed all the signs of an ischemic stroke such as weakness of the whole left side of his body‚ which can be caused by i.e congenital diseases and strokes. The ischemic stroke was found to be located in the right middle cerebral artery (right MCA) by neurologic examination. An ischemic stroke is when a tissue or an organ cannot be supplied with blood due to i.e a blood clot in the vessel. These leads to tissue death if not treated quickly enough‚ since an acute ischemic stroke can build
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The final compound which I am going to look at is 4-aminobenzenecarboxylic acid. The compound is also known as 4-Aminobenzoic acid. The molecular and structural formula of the compound is C7H7NO2 which means that the compound consists of seven carbon atoms attached to seven hydrogen atoms along with one nitrogen atom and two carbon atoms attached as a carbon-oxygen double bond. The displayed formula for the 4-aminobenzenecarboxylic acid compound is shown and it shows the formula in a ring form therefore
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We will review the financial activity of launching Orencia as a pharmacological treatment in the reduction of symptoms associated with Scleroderma. The financial activity regarding the launch expenditures are listed on table 1. A yearly activity sheet is provided to assess the stability of the product to our board of directors. An income statement‚ market share‚ and profitability ratio are listed on table 1. The ratio will examine the product positioning in the market‚ based on population and
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thrive and a localized scleroderma-like skin condition. As a child ages past infancy‚ additional conditions become apparent usually around 18–24 months. Limited growth‚ full-body alopecia‚ and a distinctive appearance are all characteristics of progeria. Signs and symptoms of this progressive disease tend to become more marked as the child ages. Later‚ the condition causes wrinkled skin‚ atherosclerosis‚ kidney failure‚ loss of eyesight‚ and cardiovascular problems. Scleroderma‚ a hardening and tightening
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changes that can occur in the integumentary system. These include inflammatory reaction of the skin and the formation of lesions‚ burns‚ cellulitis‚ dermatitis‚ folliculitis‚ furuncles‚ carbuncles‚ fungal infections‚ pressure ulcers‚ psoriasis‚ scleroderma‚ toxic epidermal necrolysis and warts. All these possible alterations mentioned applies to physiology because the integumentary system‚ which consists of the skin‚ the subcutaneous tissue below the skin‚ hair‚ nails and assorted glands protect
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Autoimmune atrophic gastritis AIHA Dermatomyositis Discoid lupus erythematosus Goodpasture’s syndrome Hashimoto’s thyroiditis ITP IDDM MS Myasthenia gravis Pemphigus vulgaris Pernicious anemia Primary biliary cirrhosis Primary myxedema RA Scleroderma SLE Thyrotoxicosis Classification Organ-specific * both lesions & autoAb’s confined to 1 organ Midspectrum * localized lesions in an organ Organ non-specific * autoAb’s organ non-specific both lesions & autoAb’s NOT confined
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