Grignard Reaction: Synthesis of Triphenylmethanol Hai Liu TA: Ara Austin Mondays: 11:30-2:20 Abstract: In this experiment‚ phenylmagnesium bromide‚ a Grignard reagent was synthesized from bromobenzene and magnesium strips in a diethyl ether solvent. The Grignard reagent was then converted to triphenylmethanol‚ a tertiary alcohol with HCl. The reaction for phenylmagnesium bromide was: The reaction for Grignard to triphenylmethanol was: In the formation of the Grignard reagent
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The SN2 reaction requires three qualities: a strong nucleophile‚ a good‚ unhindered leaving group‚ and a polar‚ aprotic solvent. For our reaction‚ we have all three bases covered. The nucleophile is an alkoxide‚ a deprotonated alcohol. Technically‚ because our alcohol is a phenol‚ the conjugate base is called a phenoxide. Phenol itself has a pKa of about 10‚ but our alcohol has more resonance opportunities‚ so the pKa is down around 8. This is sufficiently acidic for use of weak base like K2CO3 for
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The Grignard Reaction Abstract Through the use of the Grignard reaction‚ a carbon-carbon bond was formed‚ thereby resulting in the formation of triphenylmethanol from phenyl magnesium bromide and benzophenone. A recrystallization was performed to purify the Grignard product by dissolving the product in methanol. From here‚ a melting point range of 147.0 °C to 150.8 °C was obtained. The purified product yielded an IR spectrum with major peaks of 3471.82 cm-1‚ 3060.90 cm-1‚ 1597.38 cm-1‚ and 1489
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BIO 211 Lab Section 11 February 15‚ 2012 Effects of Temperature on Enzymatic Activity Abstract Temperature is a measure of kinetic energy. As this movement increases‚ collision rate and intensity‚ and therefore reaction rates‚ increase. This experiment was conducted to determine if there is a minimum temperature that increase kinetic energy and denature enzymes to slow enzymatic reactions or fail to catalyze them. The experimental results indicate an increase in temperature will increase reaction
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The experiment did not contain any form of reaction mechanism since no chemical identity had been changed. The lab demonstrates the use of chemical molecular behavior to isolate a particular set of molecules. Caffeine had already existed in the leaf itself but needed to be separated from the other chemicals. Caffeine’s chemical structure is relatively similar to the nucleic acid purine in that they use nitrogen and is bicyclic but lacks an alkene‚ amine and an amide. Caffeine has a solubility of
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Lab Techniques & Measurements Pre Lab Questions: (4pts) 1. What will you learn after completing the lab? -The experiment will introduce different level of precision and measuring to the appropriate decimal place and will be familiar with measurements and weight. 2. Write the symbols and equation used to make a dilute solution from concentrated or stock solution. - The concentration of substance is described as molarity and this can be expressed as – Molarity
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this lab). This help us view the study of Law of Conservation of Mass‚ when either side of equation is equally balanced. The calculation for formula mass helps determine if you need to convert grams to a particular substance to moles‚ from a product. Moles are numbers that are in front of formulae. E.g.‚ 6NaCl‚ 6 is the equation for this formula. A mole would help you balance a skeleton equation‚ and also allows you to calculate how many moles are needed to take part in a chemical reaction. In the
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Enzymes Reactions to Changes in Substrate and Inhibitors Benjamin J. Mora Coronado University of Texas Rio Grande Valley at Edinburgh Abstract Purpose for the experiments was to test the enzymes in various scenarios and see how changing this would affect the rate of reaction. The enzyme source used in the experiments was Turnip Extract. Concentrations of Turnip extract for activity 1 where o.5ml‚ 1.0ml‚ and 2.0 ml as for the rest of the activities 2 Through 4 stayed at a consistent concentration
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Andrea Negrete Abraham Lincoln High School Period 5 1/12/15 1/20/15 Partners: Nasya Aguilar LAB 1: Kinematic Equations and Reaction Time PURPOSE/QUESTION Apply kinematics equations for constant acceleration to find your reaction time. How much is it? How does reaction time change with practice? THEORETICAL The reaction time is the amount of time required to sense astimulus‚ analyze its meaning‚ and respond. Acceleration is the rate of change of velocity. Velocity is speed with direction
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The effect of temperature on the reaction rate: As the temperature increases it provides more kinetic energy to the molecules allowing them to move faster and with more energy the molecules can overcome the activation energy barrier and therefore the reaction occurs faster. 5. Since the proposed mechanism is a SN1 reaction the reaction got faster as the polarity increased. This is because SN1 reactions work best with polar protic solvents as they stabilize the carbocation. Therefore‚ as seen
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