questions about functions of genes involved in human diseases. Review various human disease genes w/ identified homologous in D. melanogaster the availability of genome sequences of human and model organisms has provided a good opportunity to investigate the conservation of genes responsible for heritable diseases in human such as Neurological disorders‚ developmental disorders‚ Familial Alzheimer disease‚ Fragile X syndrome‚ Tuberous sclerosis‚ cancer‚ and Tumour metastasis. The database Homophila
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cases‚ there is also a chance of colour blindness‚ difficulty adapting the eyes to dim environments‚ blurry sight while having clear peripheral vision and wavy vision. Scientists have confirmed that this is caused by a genetic mutation in the ABCA4 gene‚ which causes this tissue to begin degrading. It can also be related to
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retrovirus is a virus that has its genes encoded in RNA instead of them being encoded in DNA (it is also known as the RNA virus). Because of this‚ a retrovirus has to have its genes reverse transcribed into DNA before replication. This is carried out by an enzyme called reverse transcriptase. The retro virus upon infecting the host with its DNA can use the host cell’s machinery to replicate. The host cell cannot tell the retrovirus’s DNA from its own and so copies its genes as part of the cells own replication
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Therapeutic & Pharmaceutical proteins Biopharming‚ also known as molecular farming‚ is the production of pharmacologically active substances‚ either induced or increased through the application of genetic engineering. The first instance of artificial gene expression in an organism to produce a pharmaceutical product was the synthesis of insulin in the bacterium E. coli (Goeddel et al.‚ 1979). This type of biotechnology has since moved from microbial cell cultures to applications in eukaryotic organisms
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knowledge and understanding of these organisms and their cell products‚ we have gained the ability to control the many functions of various cells and organisms. We can now combine the genetic elements of two or more living cells using the techniques of gene splicing and recombinant DNA. Recombinant DNA is DNA that has been created artificially from two or more sources than incorporated into a single recombinant molecule. Science has come as far as having the ability of taking functioning lengths of DNA
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Hereditary Breast Cancer: The Implications of Genetic Mutations Nicole Kownacki Felician College Abstract The purpose of this paper is to examine the role genetics play related to hereditary breast cancer and the options available for risk reduction and prevention. Four published articles‚ two medical databases and a genetic focused website were examined during the process of this research. Breast cancer is one of the leading causes of death amongst women and heredity is second only to age
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BIOTECHNOLOGY RECOMBINANT DNA technology 1. This is a modern biotechnological advance ‚ in which a desired gene fragment can be inserted in to a cloning vector and the resulting DNA (Recombinant DNA) can be amplified in suitable host. 2. A vector can be a plasmid‚ cosmid‚bacterophage‚retroviruses‚ animal and plant viruses or artificial chromosomes like YAC‚ BAC‚or HAC.(Yeast artificial chromosome‚ bacterial........) 3. The rec. DNA produced can be amplified or cloned in a suitable vector
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hormones have an estrogen receptor on the surface of their cell. There are some Risk factors that cannot be changed & increase your chance of developing breast cancer. UNCHANGEABLE RISKS Family history of breast cancer Age and gender Certain genes Early menstrual cycle Onset of menopause after 55 Childbirth after 35 Women who took DES Women who take HRT Radiation therapy Some symptoms include a lump in the breast or the arm pit‚ a change in shape and size of the breast or fluid coming
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Chapter 13—Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryote Genomes Fill in the Blank |1. |Events that reshape genomes by reorganizing the DNA sequences within one or more chromosomes are known as ____________________. | |Ans: |rearrangements | | |Difficulty: 2
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Application in medicine and possible side effects. Denmeade‚ S.R. and Isaacs‚ J.T. (2002). ‘A history of prostate cancer treatment’‚ Nature Rev. Cancer‚ Vol. 2‚ pp.389–396. Reynolds‚ A.R.‚ Moghimi‚ S.M. and Hodivala-Dilke‚ K. (2003) ‘Nanoparticle-mediated gene delivery to tumor neovasculature’‚ Trends in Molecular Medicine‚ Vol. 9‚ No. 11‚ pp.2–4. Mansoori‚ G.A; Pirooz‚ M; Percival‚ M; Siavash‚ J. (2007). Nanotechnology in Cancer Prevention‚ Detection and Treatment: World Review of Science‚ Technology and
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