2013 Laboratory Instructor: Ms. Herra Grajo I. INTRODUCTION Bioinformatics is the branch of biological science which deals with the study of methods for storing‚ retrieving and analyzing biological data‚ such as nucleic acid (DNA/RNA) and protein sequence‚ structure‚ function‚ pathways and genetic interactions. It is very important since it contains large amount of information regarding biomolecules that a human mind is not able to store and process such data. There are different data bases
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central dogma of molecular biology‚ namely‚ the proteins‚ produced through translation of RNAs. Therefore‚ to study the proteins produced in an organism‚ referred to as the proteome‚ not just as products of a genome‚ but more importantly how they interact and bring about changes at the macro level‚ the field of proteomics has emerged. (1) Proteins play a pivotal role in carrying out various functions in a body at the structural and dynamic levels. Proteins as enzymes and hormones regulate the vital
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Comparative Proteomics: Protein Profiler Lab by Jonathan Thulson Biology 113 October 6‚ 2013 Lab Partner: Vernon Morris INTRODUCTION Proteomics is the study of proteins. Their functions‚ interactions with other proteins‚ cellular locations and levels at which they are expressed. The purpose of this lab was to compare the proteins present in different species of fish to be able to determine which species of fish have the closest relation. This can be determined based on which
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other groups. * DNA gets transcribe to mRNA leaves the nucleus and it gets translated into proteins in the ribosomes. * Ribosomes are complexes that are floating around or they can be attached. * Ribosomes are made up or RNA. * Ribosomal RNA helps the ribosome function as a ribosome and all of that gets made or created in the nucleolus. * Nucleolus is a densely packed of proteins and ribosomal RNA where it is reproduced. It’s not membrane bound. * Endoplasmic Reticulum
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deciding what should happen inside the city (control centre). Ribosomes- this is the industrial area of the city‚ creating building materials to extend and develop the city (proteins). Rough Endoplasmic Reticulum- these are couriers who collect the materials from the industrial site and take it to where it is needed (carry proteins). Smooth Endoplasmic Reticulum- another industrial site which creates packages to send and communicate with other cities (steroids). Mitochondria- the electricity generator
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of FAP. The mutations range from insertions‚ deletions‚ nonsense‚ and even repeats‚ which ultimately can result in a nonfunctional protein. The APC gene produces a protein known as the APC protein that is involved in regulating cell adhesion‚ signal transductions‚ and transcription activation. Park and Vogelstein (2003) stated that‚ “the localization of the APC protein is in the basolateral membrane of the colonic epithelial cells…” When mutations occur within this specific gene‚ it causes excessive
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Helical polymer of actin protein; two protofilaments. Smallest cytoskeleton diameter (3-6nm) structure Thinner‚ shorter‚ more flexible than microtubes. One basic 7subunit‚ globular actin. Structurally polar. Have fast reaction to stimuli. What super structures do they form? 1.Microvilli; structure of microfilaments lining the edge of cell 2.Stress fibers; antiparallel of actin bundles‚ contractile forces‚ wound healing ect. 3.Lamellipodia; sheet lik1.Nucleating proteins; Arp2/3 ce projections
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accessory NEF protein in HIV infection Kanokporn Tangthamvanich Department of Microbiology and Immunology University of Otago [Word count: 895] The role of the accessory NEF protein in HIV infection In human immunodeficiency virus (HIV) infection‚ there is one essential virulence protein‚ the Nef protein‚ which is identified as a negative factor due to it having a negative effect on viral replication (1). It performs critical functions in the host during the viral life cycle. The Nef protein is only
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cells are a brief explanation of the proteins in the body that regulate cell growth is also helpful in understanding cancer cells. Because our DNA carries GENSE that in turn are the blueprint for proteins produced in the body. Some of these proteins are growth factors‚ chemicals that tell cells to divide and grow. Cancer is a complex disease‚ and it is usually a combination of these abnormalities that lead to a cancerous cell‚ rather than a single mutation or protein abnormality. Next‚ Normal cells stop
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thrive in their respective environments‚ because of the function of DNA. Inside every living cell‚ DNA directs vital activities‚ such as growth‚ division‚ movement‚ respiration‚ and even death‚ by providing the instructions that cells use to build proteins. DNA gives rise to the physical and behavioral adaptations that make organisms unique. And yet‚ the chemical language in which DNA’s instructions are written is extremely simple. It consists of just four letters‚ which correspond to the four functional
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