regenerates rapidly‚ replacing damaged cells. Extensive blood supply to mucosa. Predisposing factors: H. Pylori infection 80% of peptic ulcers Smoking- reduces blood flow‚ impedes healing. High-dose corticosteroid use (inhibits prostaglandin production) More commonly seen in people with alcohol cirrhosis (alcohol stimulates gastric acid secretion)‚ chronic obstructive pulmonary disease (reduces O2 blood perfusion)‚ chronic renal failure and hyperparathyroidism (promote gastrin
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used to alleviate the pain‚ and the sensation of pain is mainly attributed to a chemical substance called prostaglandins‚ which is responsible to send a strong signal to the brain to remind the damage of the body. Working cells in the damaged area produce prostaglandins using an enzyme called cyclooxygenase 2 (COX-2)‚ and aspirin works by disturbing COX-2 functions. By doing so prostaglandins are no more produced‚ and the pain is revealed while the body damage still exists. Therefore it indicates
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Chapter 1: Cell Pathology 1-1 Which of the following accounts for differences in cells in a human body? Differences in chromatin Differences in chromosomes Differential content of DNA Differential expression of genes 1-2 Which of the following structures is not normally found in the cytoplasm of a resting cell? DNA Messenger RNA (mRNA) Ribosomal RNA (rRNA) Transfer RNA (tRNA) 1-3 Which of the following cytoplasmic organelles are not found in most all nucleated cells? Endoplasmic
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is not clear as to how and what acetaminophen does to the body in order to have its antipyretic and analgesic effects. Many proposed that acetaminophen works by inhibiting the variant COX (cyclooxygenase) enzymes that are metabolized to produce prostaglandins‚ enzymes that cause the pain. It is assumed that aspirin works by the inhibition of COX at the site of inflammation whereas acetaminophen operates on the central nervous system. Both aspirin and acetaminophen are metabolised in the liver and distributed
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4@ Argumentative Essay The act of abortion should be banned because it deliberately destroys a human life. I believe that every form of the act‚ without any exceptions‚ should be outlawed simply because abortion is merely "murdering out of convenience". From the moment that a child is conceived‚ no matter how small or underdeveloped he or she may seem‚ that child is a human being that is a separate part of its mother and a human entity all its own. And the taking of a human life by another
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by inhibiting the effects of pyrogens on the hypothalamus heat regulating centers & by a hypothalamic action leading to sweating & vasodilatation.-Relieves pain by inhibiting prostaglandin synthesis at the CNS but does not have anti-inflammatory action because of its minimal effect on peripheral prostaglandin synthesis | Hematologic: leukopenia‚ neutropenia‚ thrombocytopeniaHepatic: liver damage‚ jaundiceMetabolic: hypoglycemiaSkin: rash‚ urticaria | -Assess patient’s temperature/pain before
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Chapter 45 Hormones and the Endocrine System Lecture Outline Overview: The Body’s Long-Distance Regulators An animal hormone is a chemical signal that is secreted into the circulatory system that communicates regulatory messages within the body. A hormone may reach all parts of the body‚ but only specific target cells respond to specific hormones. A given hormone traveling in the bloodstream elicits specific responses from its target cells‚ while other cell types ignore that particular
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of heart attacks‚ diabetes‚ and to reduce pain and fever. How and why to make aspirin? Nobel Prize winner Sir John Vane discovered in 1971 that acetylsalicylic acid inhibits the biosynthesis of certain messenger molecules known as prostaglandins. These prostaglandins perform a number of different functions in the body. They play a particularly important role in the processes of pain and inflammation‚ in which they act as mediators. They are formed whenever a cell is damaged or even destroyed by
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NOTES ON MEDICAL-SURGICAL NURSING O N C O L O G Y Divina S. Fernandez RN‚ MAN Cancer – A neoplastic disorder that can involve all body organs. Cells lose their normal growth-controlling mechanism‚ and the cell growth is uncontrolled. – Cancer produces serious health problems such as impaired immune and hematopoietic (blood producing) function‚ altered gastro-intestinal tract structure and function‚ motor and sensory deficits‚ and decrease respiratory function. Metastasis – Cancer
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bengalensis has shown significant analgesic and anti-inflammatory activities‚ the probable mechanism could be by the inhibition of the PG3 synthesis. The anti-inflammatory activity may be due to either inhibition of PG biosynthesis or its anti-prostaglandin effect. Hence‚ there is a need for further investigation on this
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