Preparation and SN1 Reactivity of 2-Bromobutane Whitney Bellido Department of Chemistry‚ Illinois State University‚ Normal‚ IL 61790-4160 Submitted: April 4th‚ 2013 Introduction The overall goal of this experiment is to understand and be familiar of SN1 reactivity. We also learned how to prepare 2-Bromobutane by learning how to distill and extract this product from its organic layer. Finally‚ another goal was to specifically understand the relative reactivity of alkyl halides under SN1 conditions
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Lab 7: SN1 and SN2 Reactions Discussion/Conclusion: In this experiment the purpose of the lab was to study the relationship of structure and reactivity in nucleophilic substitution reactions by using qualitative tests of reactivity. Before the experiment began‚ students were asked to predict whether the reagents would cause an SN1 mechanism‚ SN2 mechanism‚ or both. When predicting the outcome of SN1 and SN2 reactions‚ the nature of the carbon skeleton‚ nature of the solvent‚ and the nature of
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Title: Studying SN1 and SN2 Reactions: Nucleophilic Substitutions at the saturated carbon Lab Partner: Jeszie Geronimo Objective and purpose: the purpose of this experiment is to convert a primary alcohol to an alkyl bromide using a Sn2 Reaction. Investigate some factors that influence the rate of Sn1 reactions. The second part of this lab will focus more on how unlike factors influence the rate of reactions in anSN1 reactions. The factors that we will be inspecting are the leaving groups‚ Cl-
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Substitution Reactions Materials & Methods: Materials used: 1-bromobutane 1-chlorobutane bromocyclopentane Bromocylcohexane 2-chlorobutane 2-bromobutane 2-chloro2-metylpropane 2-bromo-2-methylpropane Crotyl chloride Bromobenzene Benzyl chloride 1-chloroadamantene Methods/Techniques: Physiochemical Research: Reagent | Formula Weight | Density | Boiling Point | Melting Point | Color | 1-bromobutane | 137.023 g/mol | 1.2676 g/ml | 372-376 K | 160.7 K | Clear | 1-chlorobutane
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TA: Alekhya 6/15/15 The SN2 Reaction: Factors Affecting SN2 Reaction. Introduction In the substitution reactions‚ the leaving group from the substrate is replaced with the nucleophile. Because of the nucleophile it is called nucleophilic substitution. The lone pair of electrons‚ present on the nucleophile is used to create a new bond with the carbon atom‚ from which the leaving group was separated. There are two different mechanisms of nucleophilic substitution: SN1 and SN2. The difference between
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In this experiment‚ we used simple distillation and extraction to do synthesis of 1-bromobutane. The experiment was carried out by mixing 13.3 g of sodium bromide‚ 15 mL of water and 10 mL of n-butyl alcohol in a 100 mL round bottom flask. We cooled the mixture and added 11.5 mL of concentrated sulfuric acid. Then the mixture was heated at reflux with a short condenser for 45 minutes and then we drained out the condenser. We removed the condenser and distillation head was set up to set up the condenser
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The SN2 reaction requires three qualities: a strong nucleophile‚ a good‚ unhindered leaving group‚ and a polar‚ aprotic solvent. For our reaction‚ we have all three bases covered. The nucleophile is an alkoxide‚ a deprotonated alcohol. Technically‚ because our alcohol is a phenol‚ the conjugate base is called a phenoxide. Phenol itself has a pKa of about 10‚ but our alcohol has more resonance opportunities‚ so the pKa is down around 8. This is sufficiently acidic for use of weak base like K2CO3 for
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Reactions of Three Isomers of Butanol September 24‚ 2013 Purpose: The purpose of this lab is to test the reactions of primary‚ secondary‚ and tertiary alcohols with acid and with an oxidizing agent. Materials: chemical safety goggles dropper bottles including: butan-1-ol butan-2-ol 2-methylpropan-2-ol potassium permanganate solution‚ KMnO₄(aq) (0.01 mol/L) concentrated hydrochloric acid‚ HCl(aq) (12 mol/L) eyedropper lab apron protective gloves test tube rack Procedure:
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Reactions of Three Isomers of Butanol Purpose: To test the reactions of primary‚ secondary‚ and tertiary alcohols with acid and with an oxidizing agent. Equipment and Materials: Chemical safety goggles Lab apron Protective gloves 3 test tubes Test-tube rack Eyedropper Dropper bottles containing the following Butan-1-ol Butan-2-ol 2-methylpropan-2-ol Potassium permanganate solution‚ KMnO4(aq) (0.01 mol/L) Concentrated hydrochloric acid‚ HCl(aq) (12 mol/L) *Alcohols are flammable and
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Preparation of Acetylsalicylic Acid Abstract Acetylsalicylic acid was prepared using salicylic acid and acetic anhydride. As a result‚ a white‚ powdery substance was formed (0.1931g‚ percent yield 91.30%) and was defined by melting point (124.5 – 134.5°C) and observation of color change with ferric chloride. Introduction Acetylsalicylic acid (aspirin) is one of the most popular analgesic drugs on the market today. It also acts as an antipyretic and anti-inflammatory drug. Salicylic acid itself
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