for synthesis of the non-essential amino acids‚ amino acid remodeling‚ and conversion of non-amino acid carbon skeletons into amino acids and other derivatives that contain nitrogen. However‚ the liver is the major site of nitrogen metabolism in the body. In times of dietary surplus‚ the potentially toxic nitrogen of amino acids is eliminated via transaminations‚ deamination‚ and urea formation; the carbon skeletons are generally conserved as carbohydrate‚ via gluconeogenesis‚ or as fatty acid via
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of Shikimic Acid‚ intermediate for the production of Oseltamivir‚ the Avian Flu drug Supervised by: Dr. Reza Yegani Dr. Mohammad Hossein Sarrafzadeh Mr. Habibollah Ramezanzade by: Kaveh Yazdifard Presented on: 1385/10/3 Contents Acknowledgement Introduction Shikimic Acid & its Natural Properties Derivatives of Shikimic Acid Avian Flu Sickness‚ Medications Oseltamivir and Shikimic Acid’s Role in Synthesis Production of Shikimic Acid Extracting Shikimic Acid from the Plant
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slightly higher than the H-O-H bond angle in water because of the stronger electron repulsion between the bulky alkyl groups. Preparation of Ethers: 1. Preparation of symmetrical ethers from alcohols H2SO4 R O R + H2O 2ROH 2. Williamson Ether Synthesis R O Na - - + + + R’X R O R’ + NaX Ar O Na + RX Ar O R + NaX Involves a nucleophilic substitution reaction. Halide ion is displaced by the alkoxide or phenoxide ion. Gives best results when 1o alkyl halides are
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steps of the citric acid cycle. Differentiate between citric acid cycle and glyoxylate cycle. Relate citric acid cycle as energy source. The Central Role of the Citric Acid Cycle 3 processes play central roles in aerobic metabolism. The citric acid cycle. Electron transport . Oxidative phosphorylation. Metabolism consists of: Catabolism: the oxidative breakdown of nutrients. Anabolism: the reductive synthesis of biomolecules. • The citric acid cycle is amphibolic
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Formic acid is known to be the simplest carboxylic acid‚ and it is an important factor in chemical synthesis and occurs naturally. The chemical formula for Formic Acid is CH202‚ and is mostly found in the venom of bee and ant stings. Formic acid is clear and colorless with a pungent odor. Formic acid is used in many ways; Formic acid is used to preserve livestock. It is also sprayed on animal food and fresh hay to reduce the decay rate. It can also be used as a pesticide to protect bee
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Vol. 1 ACETIC ACID 115 ACETIC ACID 1. Introduction Acetic acid [64-19-7]‚ CH3COOH‚ is a corrosive organic acid having a sharp odor‚ burning taste‚ and pernicious blistering properties. It is found in ocean water‚ oilfield brines‚ rain‚ and at trace concentrations in many plant and animal liquids. It is central to all biological energy pathways. Fermentation of fruit and vegetable juices yields 2–12% acetic acid solutions‚ usually called vinegar (qv). Any sugar-containing sap or juice can
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Amino Acids Glycine is the smallest of the amino acids. It is ambivalent‚ meaning that it can be inside or outside of the protein molecule. In aqueous solution at or near neutral pH‚ glycine will exist predominantly as the zwitterion. Alanine is a hydrophobic molecule. It is ambivalent‚ meaning that it can be inside or outside of the protein molecule. The α carbon of alanine is optically active; in proteins‚ only the L-isomer is found. Serine differs from alanine in that one of the methylenic
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Experiment2: Preparation of Dibenzalacetone Aim: Using the cabon-cabon bond making ability in carbonyl chemistry‚ Dibenzalacetone is synthesized from 2 equivalent of benzaldehyde and 1 equivalent of acetone in a base catalyzed reaction. Physical Data1: *detailed risk and safety phrases are attached. substance Hazards‚ risks and safety practices MW (g/mol) Amt. Used Mol. mp (K) bp (K) density(g/cm^3) acetone R11‚ R36‚ R67‚ S9‚ S25‚ S26 58.08 0.24 g 0.004 178.2 329.4 0.79 benzaldehyde R22
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NUCLEIC ACIDS I.BASIC CONCEPTS II.CLASSES III.CHEMICAL NATURE IV.FUNCTION I.BASIC CONCEPTS NUCLEIC ACIDS polymeric macromolecules‚ or large biological molecules‚ essential for all known forms of life are made from monomers known as nucleotides Each nucleotide has three components: a 5-carbon sugar‚ a phosphate group‚ and a nitrogenous base If the sugar is deoxyribose‚ the polymer is DNA. If the sugar is ribose‚ the polymer is RNA. Together with proteins‚ nucleic acids are the most
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II. Synthesis This activity helps me to understand myself better by knowing what people think of me. It aims to foster self-awareness and self-improvement. I found out that my family thinks that I am a responsible person in terms of sense of responsibility. But my brother thinks I’m immature. In terms of duties at home‚ my mother and father understand that I don’t perform my duties because I’m busy with my studies. My sister thinks it too but she justified that I perform when I’m not busy. When
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