Introduction: This experiment focuses on carrying out a Perkin Reaction to synthesize (E) and (Z) isomers of α-phenylcinnamic acid. This was accomplished by refluxing benzaldehyde‚ phenylacetic acid‚ acetic anhydride and triethylamine as a base. The chemical equation of a Perkin Reaction can be seen below. The reaction mechanism for the synthesis of α-phenylcinnamic acid is shown below: Results: Theoretical Yield Therefore‚ phenylacetic acid is the limiting reagent. Table 1. Literature
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Volume 1‚ Issue 1 A Perkin Reaction: Synthesis of (E)- and (Z)-Phenylcinnamic acids Thusanth Jogarajah‚ Dr. Lana Mikhaylichenko * Department of Physical and Environmental Sciences‚ University of Toronto Scarborough‚ 1265 Military Trial‚ Scarborough‚ ON‚ M1C 1A4 Received: February 6‚ 2013; E-mail Thusanth.Jogarajah@mail.utoronto.ca Abstract – Add text here Introduction: The name of this reaction is called the Perkin’s reaction. The reaction was first used by William Perkin to create phenylcinnamic
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E XPE RIME NT 4 . 5 Reactions of acids Aim To investigate and compare some reactions of a strong acid‚ hydrochloric acid‚ and a weak acid‚ ethanoic acid (common name‚ acetic acid) Equipment Dropper bottles containing: • 0.1 M hydrochloric acid‚ HCl • 0.1 M ethanoic acid (acetic acid)‚ CH3COOH • 0.1 M sodium hydroxide‚ NaOH • 1 M hydrochloric acid‚ HCl • 1 M ethanoic acid (acetic acid)‚ CH3COOH • universal indicator solution • limewater (calcium hydroxide‚ Ca(OH)2) Marble chips (calcium carbonate
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Acetylsalicylic Acid (Aspirin) Synthesis Telow‚ AJV Sumicad‚ CJ‚ Tavanlar‚ EMMT‚ Chem 40.1‚ Institute of Chemistry‚ University of the Philippines Los Baños I. Introduction Organic synthesis is the process where a desired organic compound is constructed or prepared from commercially available materials. The objective of organic synthesis is to design the simplest synthetic routes to a molecule. Aspirin‚ also known as acetylsalicylic acid is as salicylate drug often used as analgesic
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lab‚ caproic acid was synthesized in a multi-step process that involved the synthesis of three intermediates – diethyl n-butylmalonate‚ potassium n-butylmalonate‚ and n-butyl malonic acid respectively. An IR was used to characterize the starting material‚ n-bromobutane‚ and the first intermediate‚ diethyl n-butylmalonate; while IR and NMR were used to characterize the final product‚ caproic acid. Reactions‚ Mechanism and Theory Caproic acid a.k.a n-hexanoic acid is a carboxylic acid derived from
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Synthesis of benzilic acid from benzoin utilizing a multi-step reaction. Names: Arian Karim TA Name: Sayantan Das Lab Day & Time: Thursday 7:30-11:40 Lab Section #: Abstract The main purpose of this experiment was to synthesize benzilic acid from benzoin. This requires a multistep synthesis with benzyl as an intermediate product. The first step required HNO3 as an oxidizing agent and the second step required KOH and HCl. The percentage yields of benzil and benzilic acid were 59.5%
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Experiment 4 Synthesis of Salicylic Acid Introduction Throughout history‚ botanical extracts have been used as medicines. Approximately 30% of all medicines have a plant origin. This number increases to 60% if you consider medicines that at one time were derived from plants‚ but have been synthesized in the laboratory. Salicylic acid is a white crystalline compound that can be isolated from the bark of birch trees. Since it is a valuable substance that can be isolated from nature‚ it is called
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Affects of Hydrogen Peroxide Equivalents on Green Synthesis of Adipic Acid. Andrew R. Glessman*‚ Chase W. Turner‚ Audra Cokain‚ Jacob Kindred‚ Darryl Watkins Department of Chemistry and Chemical Biology‚ IUPU‚ 402 N. Blackford St‚ Indianapolis‚ IN 46202 aglessma@umail.iu.edu April 25‚ 2014 Figure _______________________________________________________________Abstract- The synthesis of adipic acid has been a growing topic of discussion due to the harmful impact it has on the environment
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October 9‚ 2013 Partner(s): Acetylsalicylic Acid Synthesis Theory. This experiment was carried out to see how the hydroxyl group on the benzene ring in salicylic acid reacts with acetic anhydride to form an ester‚ and to make aspirin. Synthesis of Acetylsalicylic Acid occurs by protonation of carbonyl (C=O) group‚ and a nucleophilic attack of OH on the acetic anhydride. The ferric chloride test and melting point were used to test the purity of the results. A hypothesized recovery rater of above
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Experiment 8: Synthesis of Adipic Acid Performed November 8th & 10th By Jennifer Seitz Organic Chemistry 344 Section 803 Fall 2011 Objective: The purpose of this experiment was to synthesize adipic acid from cyclohexanol via an oxidation reaction that was catalyzed by sulfuric acid. Purity of the product was assessed by measuring the melting point. Physical Properties/Structures: Name | Formula | Molecular Weight (g/mol) | Boiling Point (0C) | Melting Point(0C) | Density(g/mL)
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