DNA synthesis inhibitors Nucleic acid inhibitors are chemicals which inhibit the production of nucleic acids including both DNA and RNA. DNA and RNA inhibitors inhibit enzyme action in DNA replication in the same way as the topoisomerase inhibitors we discussed earlier. Topoisomerase inhibitors (1) (10) are chemicals which interfere with the enzymes that allow DNA strands to separate and to re-join‚ a process that is required for the division of bacteria and without which DNA cannot effectively
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How organization’s overcome environmental changes? Organisations need to deal with environmental changes with appropriate strategies. First‚ organisations may choose to wait and see. Such strategy has its advantages and disadvantages. For example‚ facing a significant technological change‚ some companies may choose to integrate the new technology into their products. If they are successful‚ the rest companies’ ‘wait and see’ strategy is obviously unwise. However‚ if they failed‚ the rest companies’
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1. What is a COX-2 inhibitor? Why is it named so? How does it differ from COX-1 inhibitors? (3) COX-2 inhibitors are drugs used to treat inflammation. An example of a COX-2 inhibitor would be Celebrex. They are named COX-2 inhibitors because they inhibit cyclooxygenase-2 (COX-2) which is the enzyme responsible for inflammation. COX-2 inhibitors only affect inflammation while COX-1 would affect both inflammation and gastric acids in the stomach. COX-1 could lead to stomach issues with prolonged use
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diabetes: a consensus approach. Ball S.G.‚ Hass A.S.‚ (1994): what to expect from ACE inhibitors after myocardial infarction. Br Heart J. Biovail Pharmaceuticals‚ Inc Merck Sharp & Dohme. Vasotec® (1986): formulary information monograph. West Point‚ P.A. Merck. Prinivil® (lisinopril) (2006): tablets prescribing information. Whitehouse Station‚ N.J. D‚ Robertson J.I.‚ (1990): Angiotensin converting enzyme inhibitors and moderate hypertension Neaton J.D.‚ Kuller L.H.‚ (2005): Diuretics are color blind
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Investigating the Activity of Cholinesterase and its Inhibitors Introduction: Enzymes are highly specific biological catalysts (proteins) that influence the rate of metabolic reactions (Smith‚ 1997). They are responsible for efficiently converting substrate molecules into products required to sustain life (Grisham et al.‚ 1999). The activity of enzymes can often be effected by other endogenous or foreign factors (e.g. inhibitors). Inhibitors are able to decrease the rate of enzymatic activity
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9 Properties of Enzymes and Competitive Inhibitors. Abstract: Properties of enzymes were found in this experiment and some other factors‚ which affect enzyme activity. Enzymes are catalyst; they catalyze very specific reactions. Results relating to the active site of specific enzymes played a big role while performing this experiment. The purpose of this experiment was to fin how inhibitors affect enzyme’s activity by competing for the active site against substrates
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7. What about SGLT2 Inhibitors? SGLT2 Inhibitors would be an option of treatment for this patient. SGLT2 Inhibitors are responsible for inhibiting the reabsorption of glucose that results in excretion of glucose in the urine and ultimately the lowering of glucose levels. The patient was started on Metformin and was not compliant with the treatment. SGLT2 Inhibitors can be given as a monotherapy or as a second line therapy. SGLT2 Inhibitors would be a suitable option for the client considering
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How PPI (Proton Pump Inhibitors) Cause Anxiety? You might be feeling stressed and anxious at times and wondering why does it happening. I recommend you to check if you are taking proton pump inhibitors. Your doctor might have prescribed you proton pump inhibitors for your stomach related disease and you might be taking it for a long time. Yes‚ chronic use of proton pump inhibitors can show anxiety symptoms! When Do PPIs Prescribe? In digestive diseases like gastritis‚ there is increased secretion
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enzyme Inhibitors Irreversible enzymes are described as enzymes that require chemical activation. After chemical activation‚ the chemical reaction occurs between the target enzyme and the inhibitor. The chemical reaction results in the irreversible inhibition of the enzyme. In short‚ the enzyme catalyzes its own inactivation(Rando‚ 1974a). The purpose of irreversible inhibitors is to modifying key amino acid residues required for enzymatic activity. There are two types of irreversible inhibitors‚ which
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this experiment‚ The Effects of some Inhibitors on the Rates of Photosynthesis and Respiration by Chlorella‚ knew that the rates of photosynthesis and respiration of many plants are affected by an adding chemicals. (Yaun and Daniels‚ 2000) The authors in this experiment would like to know in which ways different inhibitors affect photosynthesis and respiration distinctly. Objectives How certain inhibitors affect photosynthesis How certain inhibitors affect respiration Hypothesis The hypothesis
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