Structure of Insulin Focus concepts The three dimensional structure of insulin is examined and sequences of various animal insulins are compared. Prerequisites • • • Amino acid structure Protein architecture Basic immunology Background Diabetics lack the protein insulin‚ which is produced by the pancreatic β-cells of the islets of Langerhans. Insulin stimulates uptake of glucose from the blood into the tissues. Diabetes is treated by replacing the missing insulin. Human insulin is produced
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Ages of concern: learning lessons from serious case reviews A thematic report of Ofsted’s evaluation of serious case reviews from 1 April 2007 to 31 March 2011 Ofsted reports have consistently highlighted that babies less than one year old and older children have been the subject of a high proportion of serious case reviews. This report provides a thematic analysis of 482 serious case reviews that Ofsted evaluated between 1 April 2007 and 31 March 2011. The main focus of this report is
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Proposed solutions for working together “Most would agree that trait represents a disposition to behave expressing itself in consistent patterns of functioning across a range of situations” (Pervin‚ 1994). Many things play into the traits that we end up with as adults. These traits have a profound effect on how we interact with groups. Difficulty can always be found when a group is attempting to work together due to variances in personality traits. The key to working together as a group is to understand
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25/01/20012 Content Generic Every child has the possibility of being hurt‚ abused‚ or put at risk of harm regardless of their gender‚ age‚ religion or ethnicity. Safeguarding includes prevention and the welfare of children with all agencies working together with children and their families‚ and to ensure all legislation‚ policies and procedures are put in place to deal with any concerns regarding children’s welfare. Children have rights to be protected from abuse‚ neglect and should be able to
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The endocrine part of the pancreas consists of pancreatic islets (islets of the Langerhans). Insulin and glucagon are hormones secreted by islet cells of the pancreas. Both of these hormones are secreted depending on the blood glucose levels. Alpha cells of the pancreatic islets secrete glucagon and beta cells of the pancreatic islets secrete insulin (Marieb‚ 2012). Insulin and glucagon are equally important in managing blood glucose‚ making sure the body functions well. Glucose‚ which comes from
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structure and function in prokaryotic and eukaryotic cells? Concept 1: Cell Structure and Function SC.912.L.14.3 SC.912.L.14.2 Content coverage LEQ: Number 1: What is the relationship between the structure and function of the major cell organelles found in a eukaryotic cell? • Structures include: cytoplasm‚ nucleus‚ nucleolus‚ nuclear envelope‚ cell membrane‚ mitochondria‚ Golgi bodies‚ vacuole‚ centrioles‚ ribosomes‚ and endoplasmic reticulum (smooth and rough) • Exclusive to plants: chloroplasts
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Science and Religion Should Work Together Many people think that science should replace religion because religion is a left over from the infancy of our intelligence and religion makes humans to not be able to think critically because they do not want to believe the facts that science could explain everything and that God does not exist. What science could not do before‚ for example‚ people like Aristotle and other ancient Greek scholars believed that the Earth was round till Isaac Newton
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Pre-Discovery Before the discovery of insulin‚ diabetes was a feared disease that most certainly led to death. Doctors knew that sugar worsened the condition of diabetic patients and that the most effective treatment was to put the patients on very strict diets where sugar intake was kept to a minimum. In 1889‚ the physician Oskar Minkowski‚ in collaboration with Joseph von Mering‚ removed the pancreas from a healthy dog to test its assumed role in digestion. The dog developed diabetes
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she lives in a flat in a city centre with her husband Bert. Mabel has had type 2 diabetes for years which has been poorly controlled by medication and diet. Mabel’s diabetes has now progressively worsened; she has been commenced on a self-managed insulin therapy plan. She is cared for by the community nursing team and her GP; she attends the regular diabetic clinic. Mabel has no other medical conditions but is currently suffering a cold. On a trip to the chemists Mabel feels unwell‚ clammy‚ trembling
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existence of cell organelles within the cell structure‚ allowing the function of the cell itself to occur; It was necessary to increase magnification by utilising an alternate source radiation (alternate to light).The result was the electron microscope‚ whereby the short wavelength and negative charge of electrons when supplied with energy allowed for greater focusing with electromagnetism. This method bends the path of the beam in the manner of a lens to light. Cell Organelles and the variation
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