acetone and silver nitrate in ethanol. Below the reaction equations 1. RX+NAIRI+NAX (X=Cl or Br) in the presence of acetone 2. RX+AgNO3+EtOHROEt+AgX+HNO3 We used three substrates primary secondary and tertiary compounds are 1-bromobutane‚ 2-bromobutane and 2-bromo-2-methylpropane respectively to react with the two nucleophiles that are sodium iodide with acetone solvent and silver nitrate with ethanol solvent. Based on lab analysis and the reaction mechanism we can predict the reactivities of the
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Abstract: The purpose of this lab was to synthesize triphenylmethanol from benzophenone and bromobenzene by the formation of a Grignard compound with the reagents bromobenzene and magnesium metal. The bromobenzene was first transformed into the Grignard compound and was then reacted with the benzophenone to make the final product. The mixture was then mixed with sulfuric acid and the organic layer was extracted via a separatory funnel. The mixture was then recrystallized from methanol and was allowed
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Lab Report: Nucleophilic substitution reaction Introduction: Alkyl halides undergo many reactions in which a nucleophile displaces the halogen atom bonded to the central carbon of the molecule. The displaced halogen atom becomes a halide ion. | | | | Some typical nucleophiles are the hydroxy group (−OH)‚ the alkoxy group (RO−)‚ and the cyanide ion (−C N). Reaction of these nucleophiles with an alkyl halide (R—X) gives the following reactions and products: | | | |
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Nucleophilic Substitution Samantha Gutierrez Nucleophilic Substitution Introduction: The purpose of this lab is to investigate how different factors affect the rate of SN1 and SN2 reactions. SN2 reactions proceed via a one step mechanism in which the incoming nucleophile attacks the electrophilic carbon center from the opposite side of the leaving group. This reaction mechanism implies that the stereochemistry of a chiral center will be inverted. SN1 reactions proceed via two steps‚ slow
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Grignard Synthesis of Triphenylmethanol Aim The aim of this experiment was to prepared Grignard reagent (phenylmagnesium bromide) from bromobenzene and magnesium‚ to use the reagent prepared to synthesise a tertiary alcohol (triphenylmethanol) by reacting reagent and ester (methyl benzoate)‚ and the product formed is analyse by infrared spectroscopy (IR)‚ melting point‚ thin layer chromatography (TLC)‚ gas chromatography mass spectrum (GCMS) and finally Nuclear Magnetic Resonance spectroscopy. Introduction
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Introduction: This lab is possible because of oxidation and reduction reactions. In organic chemistry oxidation is the loss of electron density around a carbon‚ while reduction is an increase in electron density around a carbon. More electronegative atoms such chlorine have a strong affinity for electrons while conversely low electronegative atoms have a low affinity for electrons. This unequal affinity for electrons causes an unequal
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Title: Relativities of Alkyl Halides in Nucleophilic Substitution Reactions Introduction: The purpose of this lab was to perform a comparison of relative reactivities of various alkyl halides with two different reagents‚ sodium iodine in acetone and silver nitrate in ethanol. (Below are the reaction equations). We used different substrates‚ which were primary‚ secondary‚ and tertiary. These substrates included 2-bromobutane‚ 2-bromo-2-methylpropane‚ 1-bromobutane ∞-Bromotoluene‚ bromobenzene
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The Grignard Synthesis of Triphenylmethanol Abstract: Grignard synthesis of triphenylmethanol was achieved by use of the Grignard reagent phenyl magesium brominde. The organometallic grignard reagent was synthesized by use of a reflux apparatus recrystallization techniques. Once synthesized it was used in a Grignard reaction that involved nucleophilic addition to a carbonyl in order to make triphenylmethanol. The final product was solidified and recrystallized and spectral data was
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TRANS-9-(2-PHENYLETHENYL) ANTHRACENE (A WITTIG REACTION) Introduction: The purpose of this experiment is to convert carbonyl compounds to alkenes using Wittig reaction. In this case we will be synthesizing Trans-9-(2-phenylethenyl) anthracene from benzyltriphenylphosphonium chloride and 9-anthraldehyde. We will also aim to obtaining a high percent yield and purity for the synthesis of Trans-9-(2-phenylethenyl) anthracene. The mechanism for this reaction goes thus: Experimental:
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experiment was to perform an electrophilic addition reaction by the bromination of cinnamic acid. The product of this reaction is 3-Phenyl-2‚3-dibromo propionic acid‚ which is purified by recrystallization. Cinnamic acid (3-phenylprop-2-enoic acid) is an unsaturated carboxylic acid. The electron rich π cloud (see Figure 1) in the double bond of this structure is nucleophilic and can be considered a Lewis base. It can therefore be saturated by the addition of a halogen to the double bond. Both of the
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