Sickle Cell Anemia first came into the view of the world around 1910 when Dr. James Herrick; a cardiologist‚ had a patient who complained of pain and described symptoms that sounded like anemia. He handed the case down to his assistant who‚ after taking a blood sample‚ discovered that the patient’s blood cells were not shaped like normal blood cells. When the patient’s blood cells were compared to normal blood cells‚ they appeared to be “sickle shaped”. After seeing this for himself Dr. Herrick took
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Anemia ABSTRACT The purpose of this paper is to briefly describe the initial core diagnostic questioning and core set of diagnostic testing related to the patient presenting with anemia. Subjective information and recommended testing are written with consideration of the scope of practice of the family nurse practitioner. In addition‚ three specific case studies are examined. Anemia Core set of subjective questions The healthcare provider should initially obtain a history of any previous
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Sickle cell anemia is a genetic disease that affects the shape and functionality of red blood cells. It is caused by a mutation in the DNA of the protein‚ hemoglobin‚ specifically in the beta chain. There are 531 base pairs in this DNA strand. Substitution or point mutation occurs‚ causing “GAG” to become “GTG”. This results in valine being created instead of glutamate. The mutation causes the hemoglobin to cling together in low oxygen levels and the red blood cell changes shape‚ preventing it from
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Anemia Anemia is usually defined as a decrease in amount of red blood cells (RBCs) or the amount of hemoglobin in the blood. It can also be defined as a lowered ability of the blood to carry oxygen. When anemia comes on slowly the symptoms are often vague and may include: feeling tired‚ weakness‚ shortness of breath or a poor ability to exercise. Anemia that comes on quickly often has greater symptoms which may include: confusion‚ feeling like one is going to pass out‚ and an increased desire to
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Sickle Cell Anemia (SCA) Sickle Cell Anemia (SCA) is one of a group of diseases collectively termed hemaglobinopathies‚ in which normal adult hemoglobin is partially or completely replaced by abnormal sickle hemoglobin(HgbS). Sickle Cell Anemia includes all of those hereditary disorder‚ the clinical‚ hematologic‚ and pathologic features of which are related to the presence of HbgS. Also know as SS and homozygous sickle cell disease. The most common form of SCD are: Sickle Cell Anemia – The homozygous
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Name: Nancy Jimenez BCS 210 Case Study – Case 3 – My Heart is in my Stomach This case is found in your textbook: Case Mysteries in Pathophysiology by Patricia Neafsey‚ page 19. 1. Mrs. V. is a 52 year old woman. She reported that her last period was 3 months ago but her pregnancy test was negative. Explain why the pregnancy test was done. 2. Evaluate her blood pressure and pulse rate. 3. Her history and evaluation states that she is having occasional PVC’s. What does that
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Anemia is a deadly disease; approximately 50% of people with sickle cell anemia survive to mid-40’s although fewer than 10% live more than 60 years. The devastating thong about anemia is that it can be inherited and with no cure‚ the cases of Anemia are increasing. Even though there is no cure‚ early diagnosis of low blood count can lead to better treatment‚ with better treatment‚ patients can live normal lives. However‚ the key to early diagnosis is learning what anemia is and the causes of this
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Anemia Many people link unhealthy living to topics such as obesity and cardio vascular disease but what they do not know is an unhealthy lifestyle can cause blood conditions as well. Anemia is the most common blood condition in the US it affects about 3.5 million Americans (medweb). It is an illness that occurs when blood does not have enough healthy red blood cells or hemoglobin. Hemoglobin is an iron-rich protein that gives blood its red color (Geretsen). This protein helps red blood cells carry
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Anemia A blood type is a classification of blood based on the presence or absence of inherited antigenic substances on the surface of red blood cells (RBCs). These antigens may be proteins‚ carbohydrates‚ glycoproteins‚ or glycolipids‚ depending on the blood group system. Some of these antigens are also present on the surface of other types of cells. Some of these red blood cell surface antigens can stem from one allele and collectively form a blood group system. It is called The ABO system and it
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HPRS 2301 PATHOPHYSIOLOGY CHAPTER 4 – Diseases and Conditions of the Endocrine System Orderly Function of the Endocrine System Two Systems Interaction-as one system starts‚ ends‚ or extends the activity of the other. Nervous System-creates an immediate but short lived response‚operating on the priciples of electricity through impulse conduction. Endocrine System- has a slightly slower onset and a longer duration of action‚ and uses highly specific and powerful hormones to control its
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