NITRATION OF METHYL BENZOATE Purpose: The main objective of this experiment was to synthesize methyl nitrobenzoate from methyl benzoate‚ using the mixture of nitric and sulfuric acid by performing the process of electrophillic aromatic substitution. During this reaction‚ the combination of HNO3 and H2SO4 made a nitrating solution. The crystallization was done to accomplish pure product. The melting point and Thin Layer Chromatography (TLC) were performed to test the purity of the product. Using
Premium
Rossi/Kuwata Chemistry 222 Spring 2011 Experiment 2: Spectrophotometric Determination of Iron in Vitamin Tablets (Adapted from Daniel C. Harris’ Quantitative Chemical Analysis and R. C. Atkins‚ Journal of Chemical Education 1975‚ 52‚ 550.) Experimental work to be done on February 24 + one hour scheduled on your own Notebook due on March 4 (by 4:00 pm ⇒ 20% late penalty each 24 hour period thereafter) INTRODUCTION In this experiment‚ you will dissolve the iron in a vitamin supplement tablet‚
Premium Absorbance Chemistry Laboratory glassware
Tatiana Pachova BSc‐2‚ chemistry Assistant : Chandan Dey Sciences II – lab. A Nitration of bromobenzene (n°28) 1. INTRODUCTION 1.1) 1.2) Purpose The objective of this experiment is to synthesize the p‐bromonitrobenzene (bromo‐1‐nitro‐4‐benzene) out of bromobenzene‚ by nitration. Scheme Br Br HNO3 / H2SO4 Mechanism The first step is the formation of the NO2 from the nitric acid: NO2 1.3) O O S N
Premium Sulfuric acid Solubility Nitric acid
Results: compound NaI /acetone (SN2) AgNO3/ethanol (SN1) Bromobenzene NR NR Bromocyclopentane X 2 sec Bromocyclohexane NR 4 sec 2-bromobutane 5 min 2 sec 2-chlorobutane NR X Chloroacetone 7 sec X 1-chlorobutane X X t-butyl chloride NR 6 sec Benzyl chloride 3 min X Conclusions and discussion Bromobenzene undergoes no reaction for both SN1 and SN2. This is because bromobenzene is very stable‚ and contains allylic and vinyllic bromine‚ which
Free
reaction has been focused broadly‚ and much evidence has accumulated in moving of a stepwise process‚ which proceeds with first by base-catalyzed transfer of hydrogen halide (HX) from the aryl halide — as depicted underneath for the amination of bromobenzene: The aftereffect of the end reaction is a significantly responsive midway 9 called benzyne‚ or dehydrobenzene‚ which contrasts from benzene in having two less hydrogens and an extra bond between two ortho carbons. Benzyne reacts rapidly with
Premium Oxygen Solvent Chemistry
This experiment focuses on the concept of electrophilic aromatic substitution‚ which is a type of benzene reaction. This reaction consists usually of benzene and an electrophile. The role of the nucleophile is played by the double bond on the benzene ring. IT will react will the electrophile and this reaction will form a carbon cation intermediate. With additional reactions with a base‚ the electrophile fundamentally replaces the hydrogen of the benzene. Benzene is classified as one of the countless
Premium Benzene Electrophilic aromatic substitution Nucleophile
Alkane‚ Alkene‚ Alkyne & Aromatic Learning Objectives 1. 2. 3. Determine the IUPAC name‚ common name and structure of an alkanes‚ alkenes and cycloalkanes. Identify the physical properties of alkanes. Describe briefly natural sources and importance of alkanes Describe reactions of alkanes Propose a mechanism on free radicals substitution 4. 5. 6. Describe the preparation and reactions of alkenes. 7. Propose mechanism on preparation; dehydration of alcohol 8. Define carbocation
Premium Hydrogen Benzene Methane
Grignard Reaction: Synthesis of Triphenylmethanol Hai Liu TA: Ara Austin Mondays: 11:30-2:20 Abstract: In this experiment‚ phenylmagnesium bromide‚ a Grignard reagent was synthesized from bromobenzene and magnesium strips in a diethyl ether solvent. The Grignard reagent was then converted to triphenylmethanol‚ a tertiary alcohol with HCl. The reaction for phenylmagnesium bromide was: The reaction for Grignard to triphenylmethanol was: In the formation of the Grignard reagent
Premium Magnesium Diethyl ether Oxygen
Organic Chemistry I LAB EXAM: FINAL BROMINATION OF BENZENE SYNTHESIS AND PURIFICATION OF BROMOBENZENE: PROCEDURE DATA TABLE Chemical Boiling point C Melting Point C Density g/mL Solubility Benzene 80.1 5.5 0.88 Slightly in H2O Toluene 110.6 -93 0.87 Slightly in H2O Bromobenzene 155-156 -30.8 1.50 Insoluble Dibromobenzene 220.40 87.31 0.96 Insoluble MATERIALS: Graduated cylinder Weight scale Buchner funnel Filter flask Rubber stopper Hot plate Thermometer Conical funnel Various
Premium
Grignard reagent (phenylmagnesium bromide) was performed from a bromobenzene reactant combined with magnesium and ether. Phenylmagnesium bromide was then transformed into a tertiary alcohol called triphenylmethanol‚ through addition of another compound called benzophenone‚ as well as additional ether. The end product of triphenylmethanol was analyzed via NMR and IR. Figure 1: Preparation of the Grignard agent by combining bromobenzene with magnesium and ether to produce phenylmagnesium bromide. Figure
Premium