work was to formulate‚ characterize and optimize the preparations of hybrid nanoparticles containing dapsone which is finally converted into gel for topical drug delivery. The formulations were characterized for particle size‚ zeta potential and entrapment efficiency and were optimized by applying factorial design of experiment (23). The results showed that the optimal formulation (HN 4) of dapsone loaded hybrid nanoparticles had average particle size of 277nm‚ zeta potential of 26.7 mV‚ entrapment
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materials. When particles are purposefully manufactured with nanoscale dimensions‚ we call them engineered nanoparticles. There are two other ways nanoparticles are formed. Nanoparticles can occur as a byproduct of combustion‚ industrial manufacturing‚ and other human activities; these are known as incidental nanoparticles. Natural processes‚ such as sea spray and erosion‚ can also create nanoparticles. Many important functions of living organisms take place at the nanoscale. The human body uses natural
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prevention‚ detection and treatment. We begin with a brief description of the underlying causes of cancer. Then we address preventive treatment‚ disease-time treatment‚ and diagnosis in the context of some of the most recent advances in nanotechnology. Nanoparticle science is also briefly addressed as the foundation upon which most nanotechnology cancer therapy is based. It is demonstrated how nanotechnology can help solve one of the most challenging and longstanding problems in medicine‚ which is how to
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in the colloidal state. Another important pharmaceutical application of colloid is their use as drug delivery system. The most often used colloid type drug delivery systems include hydrogels‚ microspheres‚ microemulsions‚ liposomes‚ micelles‚ nanoparticles and nanocrystals. Here we mention the main characteristics of each colloidal delivery system. Hydrogels: Hydrogel is a colloidal gel in which water is the dispersion medium. It (also called aquagel) is a network of polymer chains that are hydrophilic
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A Review of Nanomedicine Nanomedicine is the medical application of nanotechnology. The approaches to nanomedicine range from the medical use of nanomaterials‚ to nanoelectronic biosensors‚ and even possible future applications of molecular nanotechnology. Current problems for nanomedicine involve understanding the issues related to toxicity and environmental impact of nanoscale materials. Nanomedicine research is directly funded‚ with the US National Institutes of Health in 2005 funding a five-year
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Table of contents SERIAL NO: TITLE PAGE NO 1 ABSTRACT 1/24 2 INTRODUCTION 3/24 3 HISTORY 4/24 4
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EMERGING NANOTECHNOLOGY APPLICATIONS IN PETROLEUM INDUSTRY Introduction Nanotech applications & Nanoparticles have been successfully used in drilling mud for the Last 40-50 years. Recently the other disciplines of the oil industry‚ such as exploration‚ primary and assisted production‚ monitoring‚ refining and distribution‚ are approaching nanotechnologies due to its immense Potential for Confronting challenges‚ performance improvement & cost. Especially in ultra-deep water and artic environments
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conducted to investigate the properties performance such as smaller or larger in trend as well as to characterize the entrapment efficiency of drugs. The chemicals and technique used to characterize the CNPs nanoparticles are listed and the instruments used to characterize the CNPs nanoparticles are discussed. 3.2 Materials Chitosan with MW= 50‚000-190 000 Da will be used as a carrier (Sigma-Aldrich‚ UK).
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Catalytic reduction of hexacynoferrate (III) The silver nanoparticles were used in the catalytic electron transfer reaction between hexacyanoferrate (III) and sodium borohydride‚ resulting in the formation of hexacyanoferrate (II) ions and dihydrogen borate ions. The redox reaction is depicted as: [BH4] - + 8[Fe (CN) 6] -3 + 3H2O H2BO3 - + 8[Fe (CN) 6] -4+ 8H+ The reaction can even proceed without a catalyst‚ but it has been reported that it is a slow reaction‚ which follows zero-order
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others are in advanced stages of development. These nanotechnology applications include: 1- Nanofiltration membranes‚ including desalination technologies; 2- Attapulgite clay‚ zeolites and polymer filtration; 3- Nanocatalysts; 4- Magnetic nanoparticles; 5- Nanosensors for the detection of contaminants. Nanofiltration membranes Researchers are using nanomaterials ( e.g carbon nanotubes‚ alumina fibres) to build structures that have controlled shapes‚ density and dimensions for
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