10/6/2014 Case 3: Merck and River Blindness 1. Why was Merck hesitant about developing a human version of Ivermectin? Merck considered this opportunity as a high risk investment. The cost of developing the drug was estimated at $100 million. Even if it was successful to cure river blindness the victims were too poor to afford the drug. There was no way to distribute it in these rural areas were the victims were located. In addition‚ there was a possibility that people would misuse the drugs‚ which would
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Fault Tree Handbook with Aerospace Applications Version 1.1 Fault Tree Handbook with Aerospace Applications Prepared for NASA Office of Safety and Mission Assurance NASA Headquarters Washington‚ DC 20546 August‚ 2002 Fault Tree Handbook with Aerospace Applications Version 1.1 Fault Tree Handbook with Aerospace Applications NASA Project Coordinators: Dr. Michael Stamatelatos‚ NASA Headquarters Office of Safety and Mission Assurance Mr. José Caraballo‚ NASA Langley Research Center
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strategy tree analysis is one participatory tool of mapping out main problems‚ along with their causes and effects‚ supporting project planners to identify clear and manageable goals and the strategy of how to achieve them. There are three stages in this analytic process: (1) the identification of the negative aspects of an existing situation with their “causes and effects” in a problem tree‚ (2) the inversion of the problems into objectives leading into an objective tree‚ and (3) the decision of the
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Capitalizing on the abundance of waste paper ‚ the team creates a system to collect used paper from shops‚ offices‚ schools and colleges to ensure this material would be recycled and transformed into its second purpose. Then hearing impaired women‚ recovering drug addicts and victims of trafficking who struggle to find steady jobs in the community were employed to bind the paper and turn these loose sheets into lowcost‚ ecofriendly notebooks . This new product is marketed at minimal cost to college students as well
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Trees and Graphs Pat Hanrahan Tree Drawing Page 1 Why Trees? Hierarchies File systems and web sites Organization charts Categorical classifications Similiarity and clustering Branching processes Genealogy and lineages Phylogenetic trees Decision processes Indices or search trees Decision trees Tournaments Two Major Visual Representations Connection: Node / Link Diagrams Containment / Enclosure F6 G6 H6 J36 U8 B10 C30 L7 M7 V12 O4 P4 Q4 R4 S4 T4 W8 Page
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“A Poison Tree” Poetry Analysis “A Poison Tree”‚ by William Blake is a poem of four stanzas‚ with a rhyme scheme of aa-bb-cc-dd-ee-ff-gg-hh‚ and in which the poet examines the negative effects of unresolved anger. Blake cleverly presents this idea by way of an extended metaphor in order to make the point that if you let anger fester and build up‚ deplorable actions may occur. Blake also employs allusions and tone to help convey this theme. An extended metaphor is a literary device that compares
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Brand Communications Reporting Issue: IMC plan for The Banyan Tree Nichapat Fongsmut MBAII Glion Institute of Higher Education M947 Brand Communications Hand-in date 3rd October 2014 Statement of Authorship I certify that this assignment is my own work and contains no material which has been accepted for the award of any degree or diploma in any institute‚ college or university. Moreover‚ to the best of my knowledge and belief‚ it contains no material previously published or written
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Predict ‘kicks’ or bad purchases using Carvana – Cleaned and Sampled.jmp file. Create a validation data set with 50% of the data. Use Decision Tree‚ Regression and Neural Network approached for building predictive models. Perform a comparative analysis of the three competing models on validation data set. Write down your final conclusions on which model performs the best‚ what is the best cut-off to use‚ and what is the ‘value-added’ from conducting predictive modeling? Upload the saved file with
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The High Cost of Specialty Drugs; a breakdown of American’s Health Insurance Plan’s article titled‚ Specialty Drugs; Issues and Challenges Through my analysis of an Issue Brief from American’s Health Insurance Plan titled Specialty drugs; issues and challenges‚ I became cognizant of the monopoly system that pharmaceutical companies are presently ascertaining in the United States. These companies are having breakthroughs in the way they handle chronic illnesses. Consequently‚ numerous of these breakthrough
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DECISION ANALYSIS PROBLEMS Many decision analysis problems can be viewed as having three variables: decision alternatives‚ states of nature‚ and payoffs. • Decision alternatives are the various choices or options available to the decision maker in any given problem situation. On most days‚ financial managers face the choices of whether to invest in blue chip stocks‚ bonds‚ commodities‚ certificates of deposit‚ money markets‚ annuities‚ and other investments. Construction decision makers must
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