inducibly expressed only at marginal levels under condition in many tissues and is upregulated in response to a variety of stimuli‚ pro-inflammatory‚ hormones and growth factors as well as associated with inflammation and disease states. Its pivotal role in the production of prostanoids during inflammation and in cancerous states provided the rationale for the development of COX-2 selective NSAIDs.57-59
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detail - Tendinitis is inflammation of a tendon. A tendon is the thick‚ cord-like tissue that attaches a muscle to a bone. 2. How is it diagnosed? - If you have the symptoms of tendinitis‚ your doctor may order X-rays and bone scans to rule out bone damage. MRI scans can help determine the severity of damage to a tendon but are usually unnecessary for newly diagnosed cases of tendinitis. Your doctor can also assess whether you have similar problems such as bursitis (inflammation of the fluid "cushion"
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Explanation of the disease: Crohn’s disease is an inflammatory bowel disease. It’s caused by inflammation of the gastrointestinal (GI) tract and complications that can develop if the inflammation is not controlled. A. Common Symptoms: 1. Abdominal Pain: Pain often cramping and intermittent; the abdomen may be sore when touched. Abdominal pain may feel like a dull‚ constant ache depending on the location of inflammation. 2. Diarrhea: Some people with Crohn’s disease have diarrhea many times a day and need
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which can lead to other serious consequences for the patient (Gramse‚ 1983). Diverticulitis is a bugling protrusion of a mucous membrane through the wall of the colon (Marrs‚ 2006). These saclike or pouch protrusions have the potential to cause inflammation‚ obstruction‚ infection‚ and hemorrhage (Gramse‚ 1983). If left untreated‚ diverticulitis can be fatal from the above mentioned complications. The purpose of this paper is to highlight the sometimes subtle signs and symptoms of diverticulitis.
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Acne cyst treatment The typical acne pimple is a small red bump. The redness stems from the action of the body’s germ fighting cells. The white blood cells attack the bacteria in the skin‚ creating a bump on the skin. A very large‚ extended‚ all-out attack can create an acne cyst. Cystic acne can sometimes be considered severe acne‚ depending on the amount of cysts and other acne. When these large attacks take place‚ they induce the production of a sticky substance called pus. Pus appears in
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digestive system and the disease in it I did was appendicitis. I choose appendicitis because I know of it from personal experience and wanted to research more about it. Appendicitis is one of the major serious diseases of the intestines. It is an inflammation of the vermiform appendix‚ a 3 1/2-inch-long tube of tissue that extends from the large intestine. No one is absolutely certain
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predominantly affects the small bowel (in up to 80% of cases) and colon‚ but any part of the gastrointestinal tract may be involved‚ and more than one site may be affected. This disease is characterized by erosions‚ ulceration‚ full-thickness bowel wall inflammation‚ and the formation of non-caseating granulomas. Bowel involvement is frequently segmental‚ with involved segments often separated by healthy areas‚ the involved regions being referred to as “skip
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is a chronic condition of the respiratory system that causes hypersensitivity and reversible inflammation of the airways resulting in breathing difficulties (Levy et al.‚ 2006). One of the features of the disease is fixed airflow obstruction which is where the patient’s FEV1/FVC ratio is less than 0.7. The reduction of this ratio is caused by parenchymal and airway damage resulting from chronic inflammation (Nice.org.uk‚ 2010). Fixed airflow obstruction is more commonly found in severe asthma with
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limited to the colon‚ also called the large intestine. Crohn’s disease is an inflammatory bowel disease (IBD). It causes inflammation of the lining of your digestive tract‚ which can lead to abdominal pain‚ severe diarrhea‚ fatigue‚ weight loss and malnutrition. Inflammation caused by Crohn’s disease can involve different areas of the digestive tract in different people. The inflammation caused by Crohn’s disease often spreads deep into the layers of affected bowel tissue. Crohn’s disease can be both painful
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CHEMICAL MEDIATORS OF INFLAMMATION Cell derived mediators Mediator | Source | Function | Vasoactive amines | Histamine | Mast cells‚ basophil‚ platelet | Vasodilation‚ ↑ vascular permeability‚ endothelial activation | Serotonin | platelets | Vasodilation‚ ↑ vascular permeability | Eicosanoids | Prostaglandins | Mast cells‚ leukocytes | Vasodilation (PGD2‚PGE1‚E2 & PGF2-α)‚ pain (PGE2)‚ fever | Thromboxane A2 | | Promotes platelet aggregation‚ vasoconstriction | Prostacyclin
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