87‚ 88 showed strong inhibition activity both to topo II & topo I [54]. Chen et al.‚ 2013 synthesized N-(naphthalen-2-yl)acetamide and N-(substituted phenyl)acetamide bearing quinolin-2(1H)-one and 3‚4-dihydroquinolin-2(1H)-one derivatives and in vitro antiproliferative activities against a panel of human cancer cell lines including nasopharyngeal (NPCTW01)‚ lung carcinoma (H661)‚ hepatoma (Hep3B)‚ renal carcinoma (A498)‚ and gastric cancer (MKN45) was done. Compound 89
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Cent. Eur. J. Biol. • 8(10) • 2013 • 943-957 DOI: 10.2478/s11535-013-0209-6 Central European Journal of Biology New perspectives on antibacterial drug research Review Article Joanna Ziemska‚ Aleksandra Rajnisz‚ Jolanta Solecka* Laboratory of Biologically Active Compounds‚ National Institute of Public Health - National Institute of Hygiene‚ 00-791 Warsaw‚ Poland Received 14 March 2013; Accepted 10 May 2013 Abstract: Bacterial resistance to commonly used antibiotics is constantly
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177 Global Journal of Medicinal Plant Research‚ 1(2): 177-183‚ 2013 ISSN 2074-0883 Assessment of the safety of tawa-tawa (Euphorbia hirta L.) decoction as alternative folkloric medicine 1 Sharon Rose M. Tabugo‚ 1Rolliebert B. Rampola‚ 2Edgar Vasallo Jr.‚ 1Ma. Reina Suzette B. Madamba 1 Department of Biological Sciences‚ College of Science and Mathematics‚ MSU-Iligan Institute of Technology‚ Iligan City; 2 Capitol University‚ Cagayan de Oro City ABSTRACT Euphorbia hirta
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I will be informing you on a genetic disorder called Adermatoglyphia or other wise known as immigration delayed disorder. The phenotypic display of Adermatoglyphia is the lack of fingerprints‚ and a thickening of the skin‚and problems with nail formation. One other affect is the minor reduction in the ability to sweat. Adermatoglyphia can be diagnosed but just looking at your hands‚(go on look). However how often do you think about your fingerprints. If others in your family seem to have no fingerprints
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theEudragit RSPO membrane in different concentrations was cast to achieve controlled release of the drug. The absence of physiochemical interactions between VFH and the polymers was confirmed by FT-IR spectroscopy. The physicochemical parameters and in-vitro drug release studies of formulations were performed and data of optimised formulation was fitted to various kinetic models. The results indicated that suitable tri-layered transdermal patches of VFH with controlled drug release
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replaces animal experimentation with alternative methods (Stokes 1297-1298). Opponents may argue that without animal testing there would be no other options‚ but that is simply not true. Some alternative methods including computer modeling and in vitro testing are more accurate‚ more humane‚ and much
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were investigated. Methanolic and aqueous extract of leaves and fruits of P. niruri showed inhibition of membrane lipid peroxidation (LPO)‚ scavenging of 1‚1-diphenyl-2picrylhydrazyl (DPPH) radical and inhibition of reactive oxygen species (ROS) in vitro. Antioxidant activity of the extracts were also demonstrable in vivo by the inhibition of the carbon tetrachloride (CCl4) – induced formation of lipid peroxides in the liver of rats by pretreatment with the extracts. CCl4 – induced hepatotoxicity
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“The question is not‚ “Can they reason?” nor‚ “Can they talk?” but‚ “Can they suffer?” – Jeremy Betham. According to People for the Ethical Treatment of Animals (PETA)‚ over 100 million animals including mice‚ rats‚ frogs‚ dogs and cats are killed in laboratories for testing purposes. Animal testing has been a controversial subject for years now. Some believe that cosmetics‚ medicines‚ and health care products should be tested on animals to ensure their safety; on the other hand many believe that
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chosen for the optimization were Dissolution efficiency at 10 min and In-vitro dispersion
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now screen embryos for genetic disorders and select healthy embryos. Designer baby technology or reproductive genetics combines genetic screening and engineering1 processes with in vitro fertilization2 (IVF). This process is known as Pre-implantation genetic diagnosis (PGD). Steps: 1. Creating an Embryo with In-vitro fertilization (IVF). 2. Removing a single cell from that embryo within the first 5 days of creation 3. Genetically testing the cell 4.
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