relative polarities of Acetylsalicylic Acid‚ Ibuprofen‚ Acetaminophen‚ and Caffeine based on their functional groups. The most overall polar analgesic is considered to be the analgesic that contained the most polar function groups. The amine and amide functional groups are the most polar. In this experiment‚ we found that both these functional groups are found in Caffeine. As a result‚ Caffeine was the most polar out of Acetylsalicylic Acid‚ Ibuprofen‚ Acetaminophen‚ and Caffeine. Aside from Caffeine
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Addictive substances are becoming Substance abuse and addiction can changes ones life drastractly. To me substance abuse is when one over uses or depends on an addictive substance‚ and can not find a way to get away from it. Substance addiction is different than substance abuse and to me it means when someone out of control‚ which leads to harmful consequences. Many can say my siblings and I was ”sheltered” as children‚ but I believe my parents raised my three brothers and myself without bringing
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The purpose of this experiment was to answer a question: Which pill coating results in highest dissolution rates? This is important because dissolution of medicine such as ibuprofen prior to absorption maximizes effectiveness. Therefore‚ understanding how tablet coatings can affect dissolution time will be beneficial to consumers. Hypothesis: If the three types of pills are submerged in an acidic solution of pH 4.5‚ the gelatin coated capsules will dissolve quickest. This hypothesis came to be because
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also referred to as a slug. Cells within the slug then terminally differentiate into either stalk or spore to form a fruiting body. Ibuprofen (2-(4-isobutylphenyl) propionic acid‚ is a Nonsteroidal anti-inflammatory drugs (NSAID)‚ which is commonly used for the treatment of pain and inflammation. The concentration of ibuprofens found on drug stores is 100 mg of ibuprofen in 5 mL (20 mg/mL)‚ and the molecular weight is 206.28 (drugs.com). It is one of the most potent orally and highly active
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M.‚ 2001. Modelling and comparison of dissolution profiles. Eur. J. Pharm. Sci. 13‚ 123–133. Cox‚ P.J.‚ Khan‚ K.A.‚ Munday‚ D.L.‚ Sujja-areevath‚ J.‚ 1999. Development and evaluation of a multiple unit oral sustained release dosage form for S(+)-ibuprofen: preparation and release kinetics. Int. J. Pharm. 193‚ 73–84. De Brabander‚ C.‚ Vervaet‚ C.‚ Fiermans‚ L.‚ Remon‚ J.P.‚ 2000. Matrix minitablets based on starch/microcrystalline wax mixtures. Int. J. Pharm. 199‚ 195–203. Donbrow‚ M.‚ Samuelov‚ Y
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Titration: Titrations are a quantitative chemical analysis technique. They are done to tell us how much acid is required to neutralise a certain quantity of alkali. A titration is a technique in which a solution of reactant (the titrant) is added to a solution of a second reactant (the analyte) until the end point is reached. The end point of the titration is the point at which the titrant has been added in the right quantity to neutralise the analyte. Usually you can see this by adding a reagent
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Quite similar to ibuprofen‚ acetaminophen is used to treat many conditions such as headache‚ muscle aches‚ arthritis‚ backache‚ toothaches‚ colds‚ and fevers. There are other purposes this medication could be used for. Another name for acetaminophen is Paracetamol/APAP‚ while
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Rf values where the given distance from origin to solvent front measures 59 mm: 1.) acetaminophen has a Rf value of 0.48; 2.) aspirin has a Rf value of 0.64; 3.) caffeine has a Rf value of 0.22; 4.) Biogesic® sample has a Rf value of 0.48 ; 5.) ibuprofen has a Rf value of 0.73; and 6.) mefenamic Acid has a Rf value of 0.76. Thus‚ the study shows that by having equal Rf values of about 0.48‚ Biogesic®’s most active component is acetaminophen (paracetamol)‚ a relatively polar compound having a molecular
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Analgesics Krista Jinks CH 211L Section F 10/27/14 I. Abstract: The objective of this experiment was to analyze analgesic tablets by TLC to determine what analgesics they contain. The analgesics that could be in the tablets included ibuprofen‚ acetaminophen‚ aspirin‚ and caffeine. Through the use of TLC‚ unknown substance #62 was found to be Bayer Aspirin because it only contained aspirin. II. Introduction: 1. Briefly describe the process of Thin Layer Chromatography. Make it clear
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Chromatography – Analyzing Analgesics by TLC and Isolation of β-Carotene by Column Chromatography Introduction/Background: Flavonoids are an important group of additives that can be defined as pure substances either natural‚ extracted from raw materials or synthetic. Chromatography is the separation of two or more compounds or ions caused by their molecular interactions with two phases – one moving and one stationary (Weldegirma 2012). Three types of chromatography are used
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