Abstract: This experiment synthesized H-Gly-Phe-OH dipeptide using “Fmoc chemistry”. The first part of experiment was the synthesis of L-phenylalanine methyl ester hydrochloride. The methyl ester can be synthesised by reaction of thionyl chloride‚ SOCl2 and dry methanol with L-phenylalanine under reflux condition. The peptide bond was formed later in the experiment‚ where HBTU‚ DiPEA and a solution of Fmoc-Gly-OH in DMF were added to a solution of L-phenylalanine methyl ester hydrochloride in DMF
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Argumentative Synthesis “The Things They Carried” Tim O’ Brien‚ having the memories of war engraved in his mind‚ recalls the memories of his youth during battle in “The Things They Carried‚” an intriguing collection of military accounts that symbolize his attempt to resist closure from past experiences. O’ Brien’s story reflects the difficult choices people have to make in their struggle to confront the war waging inside their bodies as well as on the ground they tread. In Steven Kaplan’s criticism
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trans-platin cannot do when looking from a stereochemical perspective (9). Recently‚ by adding bulky ligands in replacement of the two amines on trans-platin‚ antitumor activity has been found‚ and even activity on cis-platin resistant tumors‚ suggesting that anticancer mechanism is not limited to lesion causing 1‚2 intrastrand
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molecule that give the molecules its properties‚ they are the centers of chemical reactivity. The structures of the functional groups used in testing are displayed in Figure 1.0. Figure 1.0 Structure of Functional Groups to Distinguish from Within the
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nanoparticles have unique properties which help in molecular diagnostics‚ in therapies‚ as well as in devices that are used in several medical procedures. The major methods used for silver nanoparticle synthesis are the physical and chemical methods. The problem with the chemical and physical methods is that the synthesis is expensive and can also have toxic substances absorbed onto them. To overcome this‚ the biological method provides a feasible alternative. The major biological systems involved in this are
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The Grignard Synthesis of Triphenylmethanol Organic Chemistry Lab II March 19‚ 2012 Abstract The purpose of this experiment was to synthesize the Grignard reagent‚ phenyl magnesium bromide‚ and then use the manufactured Grignard reagent to synthesize the alcohol‚ triphenylmethanol‚ by reacting with benzophenone and protonation by H3O+. The triphenylmethanol was purified by recrystallization. The melting point‚ Infrared Spectroscopy‚ 13C NMR‚ and 1H NMR were used to characterize and confirm
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ylide to make an alkene. This particular variation of the wittig reaction has several advantages: It gives only the trans product; it uses a much milder base that is easier to handle; and it gives a water soluble byproduct which is easy to separate from the product. The reason that these advantages occur is a change in the structure of the ylide. Instead of a tripheylphosphine ylide‚ we use a diethylphosphonate ylide. The protons are much more acidic and its byproduct is negatively charged. The
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The Grignard Synthesis of 3-methyl-3-heptanol In this experiment‚ an example of an organometallic compound which has a carbon magnesium bond will be utilized to form a tertiary alcohol. Grignard reagents have been extremely useful in the synthesis of a large number of classes of organic functional groups. Although Grignard reagents are unstable and decompose in air and moisture‚ they can be prepared and used immediately with moderate difficulty in the undergraduate organic chemistry laboratory
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INTRODUCTION This synthesis paper addresses my knowledge‚ understandings‚ analysis‚ and assessment of my experiences in this course‚ Linguistics for ESL Teachers. I am glad that we were given this task as by writing this synthesis paper‚ I can share and write out what I have learned in this course. In other word‚ I get a chance to share my experiences taking this course. For me‚ Linguistics for ESL Teachers is a very fun course. I get to learn so many things about languages‚ such as the nature
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Experiment 6: Synthesis of an Alkyl Halide Maria Alexandria Buraga Ammuyutan Institute of Chemistry‚ University of the Philippines‚ Diliman‚ Quezon City 1101 Philippines ------------------------------------------------- Department of Food and Science Nutrition‚ College of Home Economics‚ Univeristy of the Philippines‚ Diliman‚ Quezon City 1101 Philippines ------------------------------------------------- ABSTRACT ------------------------------------------------- Alcohols react with hydrogen
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