An Introduction to DNA microarrays Rebecca Fry‚ Ph.D. http://www.buffalo.edu/UBT/UBT What is a DNA Microarray? genes or gene fragments attached to a substrate (glass) Tens of thousands of spots Hybridized slide Two dyes Image analyzed 1 The Beginnings of Microarray Technology Lockhart et al.‚ 1996 Nature Biotechnology “Expression monitoring by hybridisation to high-density oligonucleotide arrays” Schena et al.‚ 1995 Science “Quantitative monitoring of gene expression
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DNA Replication Deoxyribonucleic acid (DNA) contains the genetic instructions for the biological development of a cellular form of life including some viruses. DNA is an antiparallel double helix molecule with sugar-phosphate backbone on the outer side and nitrogen bases in the inner side. The bases are paired specifically‚ also known as complementary pairing‚ Adenine (A) with Thymine (T)‚ and Guanine (G) with Cytosine (C) by two and three hydrogen bonds‚ respectively. DNA is a long polymer
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Biochemistry Exam I Terminology Boiling point is the temperature at which the vapor pressure of the liquid equals the pressure surrounding the liquid. At this temperature the liquid phase changes into the gaseous phase (also a colligative property) Melting point is the temperature at which the solid and liquid phases are in equilibrium. At this temperature the solid state changes into a liquid phase (also a colligative property) Specific heat is the amount of energy (in joules or calories) needed
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and the discovery of DNA Ralf Dahm* Max Planck Institute for Developmental Biology‚ Department 3 – Genetics‚ Spemannstr. 35/III‚ D-72076 Tubingen‚ Germany ¨ Received for publication 5 October 2004‚ revised 17 November 2004‚ accepted 20 November 2004 Available online 21 December 2004 Abstract Over the past 60 years‚ DNA has risen from being an obscure molecule with presumed accessory or structural functions inside the nucleus to the icon of modern bioscience. The story of DNA often seems to begin
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DNA sequencing From Wikipedia‚ the free encyclopedia [pic] The term DNA sequencing refers to sequencing methods for determining the order of the nucleotide bases—adenine‚ guanine‚ cytosine‚ and thymine—in a molecule of DNA. Knowledge of DNA sequences has become indispensable for basic biological research‚ other research branches utilizing DNA sequencing‚ and in numerous applied fields such as diagnostic‚ biotechnology‚ forensic biology and biologicalsystematics. The advent of DNA sequencing
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Forensic DNA Evidence DNA has become one of the most accurate tools used in law enforcement in determining guilt or innocence. DNA is different in all people it is our “genetic blueprint.” DNA is so significant to law enforcement because DNA left at a crime scene can be collected and tested to see if there is a match. It is unique because it ensures accuracy and fairness. The initial use of DNA began in Britain in 1986; the FBI used it for the first time in the United States two years
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DNA Assignment Keshia Yeates BIOLOGY 4U 1. DNA molecule with a length of 2m can fit inside a nucleus that is invisible by the naked eye by coiling around itself several times. It continues to coil even more (Supercoiling)‚ arranging itself on histones‚ which are proteins. 2. Nitrogen bases determine the traits of living organisms by coding the 20 amino acids. The order of the amino acids determines what protein is made; therefore‚ proteins are the makeup of all living organisms. Proteins regulate
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Running Head: DNA Testing DNA Testing CRJ 311 Forensics Timothy Knox November 4‚ 2012 Thesis DNA testing has become a major part of forensic science. It helps in so many areas of life. Catching criminals‚ freeing the innocent‚ determining paternity of children‚ amongst other things‚ are just a few ways DNA testing helps. It has a few cons like the financial burden of it. But in the end it is worth it. Without DNA there would be many offenders roaming the streets‚ while hundreds of innocents
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Review 2: Text DNA is a very special and important molecule that is in our life‚ DNA is found in the nucleus. DNA stores the data needed to make poly peptides‚then data in a nucleic acid is transferred to messenger RNA‚ which escapes the nucleus into a protein. According to the DNA and protein article DNA is used in many things but DNA is used to make pol-peptides. They are another word for proteins. When a cell makes a protein the direction are resembled from the part of an DNA. DNA strand and transcript
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DNA as a Key Witness Criminals‚ often unknowingly‚ leave parts of themselves behind. These pieces are not always visible to the untrained eye. Hair‚ skin‚ blood‚ and fingerprints all contain elements that are unique to each person. It is with DNA testing and fingerprinting‚ that criminals can be identified and crimes can be linked. This system of testing and matching has become the “most essential and reliable method of catching criminals” in the United States (Lynch 67). Advancing technology
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