18‚ 733-766 733 New Lead Structures in Antifungal Drug Discovery Chunquan Sheng and Wannian Zhang* Department of Medicinal Chemistry‚ School of Pharmacy‚ Second Military Medical University‚ 325 Guohe Road‚ Shanghai 200433‚ People’s Republic of China Abstract: During the past two decades‚ the incidence of invasive fungal infections has been increasing dramatically. Clinical available antifungal agents have several drawbacks such as limited potency and spectrum‚ drug related toxicity‚ non-optimal
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Efforts to Reduce the Budget Deficit Ashford University Principles of Macroeconomics ECO 203 Charles Fanning July 1‚ 2013 Efforts to Reduce the Budget Deficit For as long as people can remember‚ the United States has been in debt. Every presidents have tried to reduce our country debt. Some presidents have brought the debt down while others have watch it rise. Many people here in America are starting to wonder whether or not our country will ever be economically stable‚ or continued to be
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The argument over whether or not children should watch television has become a debate as more and more technology comes into our culture. Many researchers have produced studies to see if television programs affect a child’s ability to learn. There have been many scholar articles written about how watching television can affect the way child can learn‚ teach bad eating habits‚ and many other issues that can come from watching the “tube”‚ although these studies do not show a control on the type of
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process of distillation. Distillation is the separation of volatile substances mixed with nonvolatile substances by boiling the mixture to alter the phase of the volatile substance. The researchers used the simple distillation set up to conduct the experiment. 25 ml of The Bar Vodka was used and 7 ml of distillate was collected before a temperature of 95 degrees Celsius was reached. Collected distillate was then subjected to a flammability test to confirm ethanol content. The percent ethanol was computed
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Decisions Determine Destiny In high school‚ the opportunity to do things such as drugs‚ or alcohol presented itself. The way I was raised and with my beliefs in the LDS religion I would never do something like that. Therefore‚ I always thought‚ “If I drink or smoke‚ how will I will be able to teach my kids not to do so?” I do not want my kids saying to me‚” Dad‚ since you did that stuff‚ why can’t I?” Being an example is so important these days and I believe that the world around us is becoming
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Optimal alarm sound design: New design process for noticeable‚ but pleasant sounds Author 193 Track 3: what the beep? ABSTRACT The goal of this research is improving alarm sound design‚ focusing on the paradox of noticeable versus pleasant sounds. The characteristics of annoying sounds correspond in large extend to the characteristics of noticeable sounds. Therefore it is difficult to design an alarm sound‚ which is noticeable‚ but not annoying. A lot of studies are conducted along aspects
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Drug Abuse in America In one month‚ it will be the 100th anniversary of America’s war on drugs‚ implemented with the Harrison Narcotics Act of 1914. A full century of headstrong battle against countries held responsible of breaching our borders with drugs‚ as well as the 1.53 million American citizens annually held legally accountable. When averaged throughout the span of a year‚ a drug arrest is made every 21 seconds according to the FBI. That puts 1 in 99 adults behind bars‚ the highest incarceration
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In Stanley Milgram’s experiment‚ The Memory Project- effect on punishment on learning‚ the concept of staging in terms of what is real and not real in relation to the photographs objects and subjects‚ which is conveyed through the facilitator and the learner parallels Sontag’s concept of framing and representation In Plato’s Cave‚ and Barthes idea of posing and theater in Camera Lucida. Sontag and Barthes’s understandings of photography’s “reality” intersect in that their notion of the object in
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know when she became addicted to watching television. Actually‚ I think maybe she likes watching TV because she might have nothing to do. It could also be her grandma who always offers to turn on the TV for her. What is the real cause‚ though? I can understand if it is because she has nothing to do. But sitting in front of the TV all day? No way! I don’t get it. I have to see my niece cries everyday when her grandma turns the TV off. Why does she have to cry because of the big screen things. Moreover
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India is home to more than 12.6 million children who are forced to work in order to survive. These children are working as domestic help‚ on streets‚ in factories and farmlands silently suffering abuse. Save the Children works to end exploitative Child labour. Many children all over the world do some kind of work. You might have an after-school job‚ or maybe you help out with chores around the house. This kind of work can be great: you build skills and earn extra cash. It’s not child labour
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