increased cost‚ decreased patient satisfaction‚ and increased length of stay.21 A review of the literature was performed using the following keywords: acetaminophen‚ intravenous‚ paracetamol‚ postoperative pain‚ and analgesia. IV acetaminophen compared to oral route has shown to have a superior
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Annie’s mother asks if it is safe to give Annie children’s aspirin because she has some at home. Her husband takes it as a “blood thinner.” 1. What is your response to Annie’s mother? I would recommend using acetaminophen‚ because aspirin can make a child susceptible to Reye’s syndrome. 2. Annie will be given an antibiotic. Her mother mentions that she is allergic to penicillin. What are some checks and balances that should be in place at the physician’s office
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and tested for the purity of the drug by the melting point determination. The melting point was (135-142 C) compared to the literature melting point values for acetaminophen (169-171 C) the lower melting point show that their were still impurities in the isolated ingredient. Procedure: The acetaminophen (0.5395g) was crushed and added to a conical vial and was mixed with 2ml of methanol then shaken and let to sit till the undissolved particles settled to the bottom
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utilizing the technique of thin-layer chromatography‚ or TLC. The active ingredients of Excedrin were caffeine‚ acetaminophen‚ and aspirin with Rf values of 0.11‚ 0.38‚ and 0.61‚ respectively. The lone active ingredient of Tylenol was acetaminophen with an Rf value of 0.39. The elution sequence obtained in the experiment is as follows: ibuprofen (least polar)‚ acetylsalicylic acid‚ acetaminophen‚ and caffeine (most polar). Purpose of Experiment: The objective of this experiment is to determine the
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experiment is to investigate the composition of a simulated pharmaceutical preparation Panacetin‚ a proposed type of pain-killer. Panacetin is typically made up of sucrose‚ aspirin‚ and acetaminophen‚ but the third component in this experiment is unknown. The unknown component is suspected to be a chemical relative of acetaminophen‚ either acetanilide or phenacetin. Using techniques such as extraction‚ evaporation‚ and filtration‚ the three components will be isolated based on their solubilities and acid-base
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Introduction Chromatography is a technique used to separate a mixture into its individual components. In this experiment‚ chromatography is done by using a thin layer chromatography (TLC) plate and filter paper. The word ‘chromatography’ itself means the separation of colours. However‚ nowadays‚ both coloured and colourless compound are used in chromatography by various methods. In chromatography‚ the separation process of mixture is mainly based upon the polarity and molecular weight of sample
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better. In the article‚ “Adolescent Drug-Related ER Visits and Suicide Attempts” say‚ “Acetaminophen products were the most commonly used substances involved in hospital ER visits by female adolescents attempting suicide” (4). In other words‚ acetaminophen is a common drug female use while tries to attempt suicide. Acetaminophen is a drug that relieves pain and reduces fever and many other things. If acetaminophen are prescribed by a doctor it should not have any danger towards it. The danger only
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case of type I diabetes mellitus‚ went through a break up and he had to work long hours to support himself. He was probably under a lot of psychological and emotional stress‚ suffering from ’tension headache’ and took an over dose of Panadol or acetaminophen with alcohol. According to food and drug agency (2009)‚ a combination of these can cause acute liver failure‚ something that needs to be worked on in this case. Jeremy is taking insulin aspart (NovoRapid) which is rapidly acting insulin and insulin
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analysis by having us do a TLC analysis of analgesics to figure out their main chemical components. Calculations: 1.) Rf = Distance spot traveled/ distance solvent traveled Results: Table 1: TLC Analysis Analgesic Drugs | Rf Value | Acetaminophen | 0.323 | Aspirin | 0.597 | Caffeine | 0.081 | Unknown 154 (Plate 1) | 0.081‚ 0.306‚ 0.597 | Ibuprofen | 0.698 | Salicyclamide | 0.587 | Unknown 154 (plate 2) | 0.079‚ 0.397‚ 0.587 | Discussion: The goal of this experiment was
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Shields 2016). The most common side effects are sedation and constipation (Wilson‚ Shannon‚ Shields 2016). Oxycodone can have life-threatening side effects such as respiratory depression and hepatoxicity‚ which is seen if oxycodone is combined with acetaminophen (Wilson‚ Shannon‚ Shields 2016). Oxycodone can interact with alcohol and St. John’s wort to increase sedation (Wilson‚ Shannon‚ Shields 2016) and “use of enzyme inducers such as rifampicin‚ St John’s wort and carbamazepine should be avoided because
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