Anatomic Pathology / HER-2 DETECTION BY CISH IN BREAST CANCER Comparison of Fluorescence and Chromogenic In Situ Hybridization for Detection of HER-2/neu Oncogene in Breast Cancer Deepali Gupta‚ MD‚1 Lavinia P. Middleton‚ MD‚2 Marion J. Whitaker‚ CT(ASCP)‚3 and Jacki Abrams‚ MD1‚3 Key Words: HER-2/neu; Fluorescence in situ hybridization; Chromogenic in situ hybridization; Breast cancer; CISH; FISH DOI: 10.1309/P40P2EAD42PUKDMG Abstract Determination of HER-2/neu oncogene amplification
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Biology‚ 7e (Campbell) Chapter 15: The Chromosomal Basis of Inheritance Chapter Questions 1) Chromosomes and genes share all of the following characteristics except that A) they are both present in pairs in all diploid cells. B) they both undergo segregation during meiosis. C) their copy numbers in the cell decrease after meiosis‚ and increase during fertilization. D) they are both copied during the S phase of the cell cycle. E) they both pair up with their homologues during
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EXAM1 Q1. How many chromosomes are in a typical red blood cell taken from a normal person? Zero Q2. The degree to which a trait is expressed in individuals is the expressivity of the trait. Q3. In pedigrees‚ a male individual is symbolized as a square. Q4. The chromosomal structure that anchors the spindle fiber to the chromosome is centromere. Q5. The short arm of a submetacentric chromosome is symbolized as the p arm. Q6. Genetic diseases transmitted only by a mother to both sons and daughters
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GENETICS JARGON Alleles (allelomorphs) Alternative forms of a particular gene. There can be several alleles of a particular gene in the population‚ but only 2 alleles can be inherited by a single individual. For simplicity much literature aimed at the general reader uses "gene" where it means "allele". Allelic Series A series of alleles that are all mutant forms of the same gene and are at the same locus (same position on the chromsome). Alternate Heredity Mendelian inheritance involving
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Directory of Brazilian Life Science Companies AGRICULTURE Companies that develop/commercialize transgenic seeds and plants‚ biological pest control‚ plant cloning‚ molecular diagnostic‚ biofertilizers‚ genetic improvement‚ catalysts and bioenergy companies. AgroGenética Brief description: AgroGenética operates in the identification and quantification of transgenic products and detection of residues in feed products. Telephone: +55 (31) 3891-0817 City: Viçosa State: Minas Gerais Contact: Wilton
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Medicine \ Microbiology Careers The need for qualified microbiologists continues to grow‚ both for basic research and practical applications. Many microbes have yet to be discovered. In addition‚ microbiologists are still studying how the known microbes function. As a result‚ the field of microbiology has virtually unlimited potential. Microbiologists are needed across many industries‚ including in academic‚ technology‚ industrial and environmental organizations. Several career paths exist for
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Name: ________________________ Class: ___________________ Date: __________ ID: A Genetics test questions Multiple Choice Identify the letter of the choice that best completes the statement or answers the question. ____ 1. Pea plants were particularly well suited for use in Mendel’s breeding experiments for all of the following reasons except that a. peas show easily observed variations in a number of characters‚ such as pea shape and flower color. b. it is possible to completely control matings
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CHANTIX® (varenicline) Tablets DESCRIPTION CHANTIX® tablets contain the active ingredient‚ varenicline (as the tartrate salt)‚ which is a partial agonist selective for α4β2 nicotinic acetylcholine receptor subtypes. Varenicline‚ as the tartrate salt‚ is a powder which is a white to off-white to slightly yellow solid with the following chemical name: 7‚8‚9‚10-tetrahydro-6‚10-methano-6H-pyrazino[2‚3h][3]benzazepine‚ (2R‚3R)-2‚3-dihydroxybutanedioate (1:1). It is highly soluble in water. Varenicline
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Why women generally get breast cancer rather than other cancers? ABSTRACT Background It is evident that when a person is affected with disease‚ he becomes aware of some treatment and he likes to follow the instruction of the physicians and prescription of him and he also makes some restriction on all over the lifestyle of him. The advanced technology is fast enough to eradicate the problems of human beings and they are easy to find out some solutions and some
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HUMAN GENE THERAPY 22:1–10 (August 2011) ª Mary Ann Liebert‚ Inc. DOI: 10.1089/hum.2011.087 Review Zinc-Finger Nucleases for Somatic Gene Therapy: The Next Frontier 1 Shamim H. Rahman‚ Morgan L. Maeder‚2‚3 J. Keith Joung‚2‚3‚4 and Toni Cathomen1 Abstract Zinc-finger nucleases (ZFNs) are a powerful tool that can be used to edit the human genome ad libitum. The technology has experienced remarkable development in the last few years with regard to both the target site specificity and the
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