Lupus: When the Body Attacks Cassandra E. Gilles Fortis College (Miami‚ FL) Abstract Systemic Lupus Erythematosus also known as Lupus or SLE for short is a long-term chronic inflammation autoimmune disease. The cause is unknown but research suggests that both genetic and environmental factors are involved. Predispositions such as race‚ gender and age increase the likeliness of being diagnosed with lupus. Lupus is difficult to diagnose because the common signs and symptoms seem to mimic other
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Introduction Systemic Lupus Erythematosus (SLE) is an autoimmune disease that composes many factors that contribute to the manisfestations of SLE. These factors include genetic and epigenetic regulation of gene expression‚ environmental factors‚ hormones‚ and a dysfunction in the immune system. It is estimated that about 1.5 million patients‚ and many other patients worldwide‚ have lupus. The survival rate of SLE patients improved from 50 % to 90% over the last 40 years from an estimated 5-year
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Systemic Lupus Erythematosus Systemic Lupus Erythematosus‚ or often called lupus‚ is an autoimmune disorder that affects the skin‚ joints‚ kidneys‚ brain‚ and other organs. Lupus is a chronic inflammatory disease that happens when your body’s immune system attacks its own tissues and organs. Lupus can be difficult to diagnose because of the signs and symptoms often mimic other diseases. The most distinct sign of lupus is a facial rash that resembles a butterfly unfolding across both cheeks.
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Systemic Lupus Erythematosus Systemic lupus erythematosus‚ often known simply as lupus or abbreviated to SLE‚ is a systemic autoimmune disease or an autoimmune connective tissue disease that can affect any part of the body. As occurs in other autoimmune diseases‚ the immune system attacks the body ’s cells and tissue‚ resulting in inflammation and tissue damage. It is a hypersensitivity reaction of the type III variety‚ caused by antibody-immune complex formation. There are several explanations
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INTRODUCTION: - Systemic lupus erythematosus (SLE) is an autonomous disorder with variety of autoantibodies (double stranded DNA [dsDNA]‚ ANA). It causes inflammation diffusely through the body (skin‚ brain‚ kidneys‚ and joints) and also the blood. Lupus has varied abnormal blood tests related to it (anemia‚ anti-Sm‚ anti-phospholipid antibodies)‚ however this is often not a similar issue as knowing what causes lupus. Its cause could be a mystery. The etiology of lupus is unknown‚ however multiple
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Systemic Lupus Erythematosus Treatments Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease. It harms the skin‚ joints‚ kidneys‚ lungs‚ nervous system‚ and the serous membranes (Specchia et al‚ 2014‚ p.1). The symptoms in patients most commonly involve a mixture of skin conditions that affect one’s muscles‚ bones‚ and joints. Furthermore‚ SLE can have blood and blood serum symptoms. Women are more commonly affected than men‚ and the disease is diagnosed in patients aged
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Systemic Lupus Erythematosus (SLE) is an autoimmune heterogenous disease‚ meaning it is caused by many genes and alleles and variations of those genes. According to the Journal of Rare Diseases‚SLE is characterized by the presence of autoantibodies against nuclear antigens (1). An estimated 1 per 1000 individuals are affected overall‚ qualifying SLE as a rare disease. Females are more affected at a female to male ratio of 10:1. Researchers believe that‚ as many females become susceptible during pregnancy
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What is Systemic Lupus Erythematosus (S.L.E) Systemic Lupus Erythematosus is a chronic autoimmune disease which causes inflammation of your joints‚ tissues‚ and organs. The inflammation presents itself as heat‚ pain‚ swelling and redness. SLE is a variable disease that doesn’t take any one particular course; therefore its unpredictability makes it even more devastating. No two people will experience the same disease symptoms or severity level. As S.L.E progresses there will be periods of
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Systemic Lupus Erythematosus (SLE) is an autoimmune disease characterized by acute and chronic inflammation of various tissues of the body. Like other autoimmune diseases‚ lupus occurs when the body’ own tissues are attacked by its own immune system. Symptoms of lupus can vary from one person to another‚ and may come and go. There is no total cure of lupus. The goal of treatment is geared toward symptoms relief to protect the vital organs of the body. Better see your doctor immediately if you suspect
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Systemic Lupus Erythematosus (SLE) is an autoimmune disease that can potentially affect all of the systems of the body. This disease can often be seen along with other autoimmune disorders. SLE is characterized by the antibodies of a patient beginning to attack normal healthy cells. “The Lupus Foundation of America estimates that 1.5 million Americans‚ and at least five million people worldwide‚ have a form of lupus‚” The Lupus Foundation of America (2015). It is often difficult and can take up
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