is when there is an overproduction of collagen fiber‚ which causes sclerosis (hardening) and fibrosis (scarring) in the skin. Collagen fibers are a type of protein that have great strength and flexibility for certain structures of the body. They are one of the biggest components that make up the connective tissue‚ which is why this disease is known as a connective tissue disorder. Connective tissue makes up all the structures of the human body‚ meaning collagen fiber are found throughout the body
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the disruption of the integrity of collagen. Ehlers-Danlos is not rare‚ but it is rarely diagnosed. While there is no cure‚ there are treatments that can help alleviate your symptoms. Here’s what you need to know. Ehlers-Danlos syndrome Ehlers-Danlos is a group of six or more genetic disorders. If you have it‚ chances are high that someone else in your family has had it or does have it since it is hereditary. Collagen is the necessary glue of your body. Collagen is a protein that allows your tissues
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Merkel’s cell’s - not clearly known 2. Dermis The dermis is made of two layers - papillary layer ( upper) made of a thin array of collagen fibers - reticular layer (lower) made of thick collagen fibers that are set parallel to the surface of the skin. 3 types of tissue that exist throughout - not in layers. The types of tissue are: - collagen - elastic tissue - reticular fibers Special Dermal Cells - The hair follicles – attached by the erector pili muscle. - Sebaceous (oil)
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The cause of scleroderma is unknown. People with this condition have a buildup of a substance called collagen in the skin and other organs. Collagen that is buildup and not normally broken down causes the accumulation of collagen called fibrosis. In SSc‚ excess collagen causes fibrosis in the heart‚ lungs‚ and the muscles that line the GI tract . The collagen causes fibroblasts within the collagen to overactive causing scar tissue damage‚ decreased flexibility‚ and malfunction of the organ involved
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Professional tattoos causes the breakage of the skin‚ triggering the automatic response of wound healing. Otherwise the standard removal of ink using laser can produce scars depending on the depth of the colour. Scarring tissue heavily involves fibroblasts and the specialised myofibroblast role is to replace the ECM components. The scarring and aging of the skin results in increase friction and declined mechanical properties-compression‚ tension and elasticity (Richard Wong). Wound healing can be
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protein‚ which is way cheaper and lighter than other sources of protein such as meat and peanut butter. Also jello takes 4 months to expire and over a year if it was refrigerated. Thecoconutmama voices‚ “ Did you know that our bones are made up of collagen? We hear often that calcium is needed for healthy bones but
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store calcium as well as mineral phosphorus 7.2 2. What cell synthesizes the organic matrix of bone? What is the organic matrix of bone composed of? Osteoblasts synthesize the organic matrix of bone. The organic matrix of bone is composed of collagen‚ glycosaminoglycan‚ proteoglycans‚ and glycoproteins 3. What is the inorganic matrix of bone composed of? Composed of calcium‚ phosphorus‚ bicarbonate‚ citrate‚ magnesium‚ potassium‚ sodium‚ and hydroxide ions 4. What two organelles do you think
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along their free surface. Lying adjacent to the basal surface of an epithelium is a thin supporting sheet called the basal lamina. This noncellular‚ adhesive sheet consists largely of glycoproteins secreted by the epithelial cells plus some fine collagen fibers. The basal lamina acts a selective filter that determines which molecules diffusing from the underlying connective tissue are allowed to enter the epithelium. The basal lamina also acts as a scaffolding along which epithelial
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exposed and platelet adhesion occurs because of reaction of collagen. The thrombus is adherent to the surface of plaque. 2- the second process is deep endothelial fissuring‚ the plaque cap tears ( ulcerates‚ fissures or ruptures)‚ allowing blood from the lumen to enter the inside of the plaque itself. The core with lamellar lipid surface‚ tissue factor ( which triggers platelet adhesion and activation ) produced by macrophages and exposed collagen‚ is highly thrombogenic. Thrombus forms within the plaque
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production of a major protein in bone and connective tissue‚ defects in these genes reduce the amount of collagen in our bodies‚ weakens the connective tissues‚ and creates future problems with the growth of bones. More than ninety percent of all cases of OI come from mutations in the COL1A1 and COL1A2 genes‚ located on chromosome 17 and 7 in the bodies. Both of these genes instruct proteins for collagen assembly. Thus‚ problems on the COL1A1 and COL1A2 genes ultimately create the hallmark of OI‚ brittle
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