Lab Report Macrocyclic Synthesis (Heme Analog) I. Purpose of Experiment and Introduction The purpose of this lab experiment is to prepare meso-tetraphenylporphin (TPP) and its copper‚ cobalt or zinc complex by condensing benzaldehyde with pyrrole in boiling propanoic acid. II. Introduction and Background There are two types of proteins that function as oxygen carriers: myoglobin (stores the oxygen) and hemoglobin (present in red blood cells and is responsible for oxygen transport)
Premium Distillation Chemistry Acetic acid
Synthesis of Acetanilide By: Rick Whitely April 9‚ 2013 Organic Chemistry Lab 1; Professor J. Hutchison Recrystallization is a common method of purifying organic substances through the differences in solubility at different temperature. In this experiment‚ acetanilide was produced by acetylation of aniline with acetic anhydride. The crude acetanilide was dissolved in a solvent in a heated water bath. The solution was cooled slowly in an ice bath as crystals form out. As the compound crystallizes
Premium Amine Oxygen Acetic acid
CHEM3412 Synthesis of a Porphyrin Porphyrins are hetereonuclear‚ macrocyclic compounds that play an important role in living organisms. Examples include the non-protein heme portion of hemoglobin in animals whereby the lone pairs on nitrogen can bind to the oxygen-carrying iron. In plants‚ chlorophyll uses the vast conjugation to allow absorption of light for photosynthesis. The characteristic colors of porphyrins is also due to the conjugation. An examination of the porphyrin structure
Premium Electrophilic aromatic substitution
Experiment 2 and 3: Synthesis of Aspirin and Determination of Melting Point A. Abstract Aspirin is the common name for the compound acetylsalicylic acid‚ widely used as a fever reducer and as a pain killer. The first part of the experiment aims to synthesize aspirin from the reaction of salicylic acid with acetic anhydride with the aid of phosphoric acid as a catalyst. The second part of the experiment aims to assess the purity of aspirin through the determination of its melting point and
Free Aspirin Acetic acid Carboxylic acid
Jewellyn G. Diola; ladyjewellyndiola@yahoo.com Abstract Synthesis of 3‚4-dihydro-3-(p-methylphenyl)-1‚2-(2h)-benzoxazine involves the nucleophillic addition of the 1 °amine group upon the carbonyly group of the salicylaldehyde‚ the reduction of imine to amine and the addition of paraformaldehyde to proceed ring closure. The experiment prepared the product through Mannich reaction‚ a multicomponent condensation synthesis between ketone‚ aldehydes‚ enols and amines. Biosynthesis of benzoaxazines
Premium Amino acid
A Synthesis of Safrole and o-Safrole W.H. Perkin & V.M. Trikojus J. Chem. Soc. 1663 (1927) HTML by Rhodium No direct synthesis of safrole has been recorded‚ the most recent attempt being that of Baker and Robinson (JCS‚ 1925‚ 127‚ 1424)‚ who distilled the product of the action of silver oxide and water upon gamma-piperonylpropyltrimethylammonium iodide‚ but obtained isosafrole‚ the double bond moving into the position of greater stability. Kawai (Sci. Papers Inst. Phys. Chem. Res.‚ 1925‚ 3‚ 263)
Premium Sodium Ethanol Sodium sulfate
Identifying sites of protein synthesis in Chlamydomonas using erythromycin and cyclohexamide as protein synthesis inhibitors. October 16‚ 2009 Introduction: In living cells‚ prokaryotic or eukaryotic‚ the synthesis (construction) of proteins is accomplished by similar machinery. Amino acids‚ ribosomes‚ messenger RNA (mRNA)‚ and transfer RNA (tRNA)‚ are all necessary for the building of functional proteins in a cell. Ribosomes are the site of protein synthesis in a cell‚ and there are two
Premium Protein Cell DNA
Gringard Synthesis detailed procedure and scheme of the apparatus any changes to the original procedure‚ actual masses‚ and obs yield calculations and mp Discussion outline Grignard rxn (what is it used for‚ why important‚ the mechanism) Reaction set up (important details) How can the rxn be activated Second step: rxn of the Grignard reagent with acetophenone‚ quenching with ammonium chloride Isolation of the product‚ identification Possible or actual sources of error Part one of our experiment
Premium Magnesium Chemistry Diethyl ether
Synthesis of DEET Abstract: For this experiment m-toluic acid was reacted with thionyl chloride resulting in a nucleophilic acyl substitution which could then be used to create DEET with excess diethyl amine (Figure 1). This was done by adding diethyl amine drop wise using a seperatory funnel which resulted in a gas formation which was controlled with a condenser attached to a gas vacuum. The resulting mixture was then washed to remove excess acids and bases and rotovapped. DEET was synthesized
Premium Chlorine Alcohol Functional group
Abstract Introduction The acylation of the α carbon position of a carbonyl group is one of the greatest breakthroughs that has benefited chemists in organic synthesis particularly when in need of building a carbon skeleton of interest in a molecule. For one to be able perform this acylation technique‚ there are two mar approaches which are employable. The first method involves the deprotonation of the α-Carbon atom which has a pKa known to be ̴20 through the use of a strong base for instance
Premium Functional group Amide Functional groups