The Leicester School of Pharmacy Faculty of Health and Life Sciences PHAR1603 Pharmaceutical Chemistry Module Handbook 2014-15 The Leicester School of Pharmacy MPharm (Hons) The Module Team Room Email address Phone (0116 …) Dr G Hall (GH‚ Module Leader) HB2.25n ghall@dmu.ac.uk 257 7278 Dr P Bremner (PB) HB1.03 pbremner@dmu.ac.uk 257 7922 Dr J Dixon HB1.16 jdixon@dmu.ac.uk 207 8117 Prof. Katherine Huddersman (KH) HB2M1 huddzeo1@dmu
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that Awful Smell”? - Bromine There are 118 known elements to man‚ and each of them differ in its own way. They vary from weight‚ structure‚ color‚ and much more‚ but many of them are similar to others and can be grouped accordingly. One element that varies drastically from others is one whose stench is so horrible‚ that the original name of the element was changed from muride to bromos‚ which means “stench” in Greek. Thus‚ bromine was named. Like many other known elements‚ bromine was discovered by
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Bromine’s physical state is a liquid‚ and it’s density is 3.122 g/cm^3. Bromine has a boiling point of 137.8ºF‚ which is also 58.8ºC. isotopes (Br-80)- 69-97 It’s melting point is 19ºF‚ also is -7.2ºC. Bromine is not very reactive as fluorine or chlorine but it’s way more reactive than iodine. Bromine is a nonmetal‚ and it’s a natural element. Bromine is known to be a very dense reddish brown toned liquid when formed compounds with elements such as chlorine‚ it works as a bleaching agent. It evaporates
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Alkanes The reaction between alkanes and fluorine This reaction is explosive even in the cold and dark‚ and you tend to get carbon and hydrogen fluoride produced. It is of no particular interest. For example: The reaction between alkanes and iodine Iodine doesn’t react with the alkanes to any extent - at least‚ under normal lab conditions. The reactions between alkanes and chlorine or bromine There is no reaction in the dark. In the presence of a flame‚ the reactions are
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Exercise 5 Comparing the Reaction Rates of Alkanes and Alkenes Group # 4 Members: Pangan‚ Sam Margarette Perales‚ Angelica Ibay‚ Sophia Irigan‚ Sharien May Sorensen‚ John Antonio Ocan‚ Emmanuel Submitted to: Ms. Ginalyn Cuenca Mr. Neil Abreo Date: December 6‚ 2012 Introduction Alkanes are hydrocarbons with only single bonds between the atoms. Saturated hydrocarbon is the other term for it. They are used as fuels because they are non-reactive and also do not conduct electricity
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Experiment: Comparing reactivities of alkanes and alkenes Aim: To compare the reactivities of an alkane and an alkene with bromine water and a solution of potassium permanganate (KMnO4). Equipment: • 4 test tubes • Test-tube rack • 4 pipettes Safety: safety glasses must be worn to prevent injury to the eyes. Ensure room is well ventilated whilst using the hydro carbons. Method: 1. Place 1 ml of sample A (cyclohexane) into a test tube containing 4 mls of the bromine water solution. Record observations
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Hydrocarbons – Methane (Alkanes) Introduction to Hydrocarbons – Methane Carbons have the ability to form many different compounds. Compounds of carbon that only contain carbon and hydrogen are known as hydrocarbons. Most hydrocarbons naturally occur in the mixture crude oil. There are three main types of hydrocarbons‚ alkanes – saturated hydrocarbons made up of only single bonds‚ alkenes – unsaturated hydrocarbons with one or more double bond/s‚ and alkynes – unsaturated hydrocarbons with one or
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Cyclic ( Open chain) Alicyclic Aromatic Alkanes Alkenes Alkyne Cycloalkanes Cycloalkenes Cycloalkynes Alkanes:- Paraffins General formula CnH2n+2 sp3 hybridisation C–C bond length 1.15 4 A0 Chemically unreactive Show chain‚ position and optical isomerism. Heptane has 9 isomer‚ Octane 18 and Decane 75. Nomenclature: 164 Preparation:- Wurtz reaction:- Follow mainly free radical mechanism Useful in preparing an alkane containing even number of carbon atoms Stepping
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Experiment #3 Mark A. Bruder 07. T.A. Michael Hall Alkanes: Chlorination Introduction: The purpose of this experiment is to determine the reactivity of hydrogen atoms on a carbon chain using free radical chlorination. In this experiment 1-chlorobutane will be chlorinated with the combination of sulfuryl chloride and ABCN as an initiator to produce the chlorine radicals. The combination of 1-chlorobutane and sulfur chloride will produce four dichlorobutane
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Chris Holet 7 – 20-12 Steriochemistry of Bromine Addition to trans-Cinnamic Acid Purpose: To carry out the addition of bromine to trans-cinnamic acid and to identify the product from its melting point. Molecular Structures and Chemical Reaction(s): Results and Calculations: Table of reagents Name Density (g/ml) Amount used Amount # moles Bromine (excess) Trans-cinnamic Acid 1.246 g/cm3 0.148g – do conversion Dichloromethane 1‚3266 g/cm3 -
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