Coagulation factor V (FV) circulates in the bloodstream in an inactive form (procofactor) and is activated to factor Va (FVa) by thrombin. Thrombin cleaves away the large inhibitory B-domain of FV which resolves the molecule into a heterodimer that is stabilized through non-covalent interactions between heavy (A1-A2) and light (A3-C1-C2) chains. A recombinantly expressed truncated B-domain variant of factor V (FV-DT) exhibits constitutive FVa-like activity even in the absence of proteolysis. FV maintains
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Henry V – William Shakespeare There can be little doubt that Shakespeare intended to present his protagonist in “Henry V” as the popular hero-king. His efforts are mainly concentrated on the portraiture of this “star of England”‚ King Henry‚ whom he deliberately chose out of the page of history as the finest representative of the best distinctive type of English character. He wanted his play to lead triumphantly to an English victory against overwhelming odds at Agincourt. What is not agreed among
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Plessy v. Ferguson In 1896 the Louisiana Supreme Court was challenged with a case that had the potential to tear apart racial segregation in our country. The central question that revolved around this court case was whether or not segregation amongst whites and blacks was still equal. The decision made by the court prolonged unnecessary social/racial inequality‚ oppression‚ hate‚ and violence in our country. The court’s ruling had immutable repercussions that greatly scarred our nation’s history
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involved in establishing medical standards of care based on facts of a single case rather than on the standards of the profession (King‚ p.1236-37). In a sense‚ the issue is approached from a semantic and factual rather than medical standpoint. Helling v. Carey is a good example of such a case which excited considerable comment in the medical and legal fields. In the final analysis the case is considered unique and controversial mainly because the court dismissed the standards of medical profession and
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saw some of the most important cases in the history of the United States and many are still in effect today. The Warren court heavily believed in improving the civil liberties of the people. His ruling on Gideon v. Wainwright is no different. In 1963‚ the monumental case of Gideon v. Wainwright was taken to the Supreme Court. This case involved the 6th amendment of the constitution. The case began as a simple accusation of Gideon of a burglary in Panama City‚ Florida. After being accused‚ Mr
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MBA560 COUGHLIN v TAILHOOK 112 F.3d 1052 (1997) United States Court of Appeals‚ Ninth Circuit Facts: During a convention at the Las Vegas Hilton in September 1991‚ Navy Lieutenant Paula Coughlin was attacked by a group of men in a hotel hallway. The resulting post-traumatic stress disorder and other problems related to the attack eventually hampered her ability to perform her duties. Ultimately‚ she resigned from the US Navy. Coughlin brought action against the Hilton Hotels Corporation
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ENGLISH LITERATURE ORAL SAC Cal Stanley Edward Albee first published his famous American play‚ Who’s Afraid of Virginia Woolf‚ in 1962. The play took to the stage with critical praise and can be described as one of the greatest American plays ever written. Four years later‚ Director and Producer Mike Nichols adapted the play to the silver screen with one of Hollywood’s most acclaimed screenwriters Ernest Lehman‚ the film released much like the play before it‚ to a highly positive reception
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Case Name: Missouri v. Jenkins 491 U.S. 274 (1989) United States Supreme Court Facts: The attorneys and associates for plaintiff‚ Kansas City Missouri School District‚ had been litigating a school district segregation case since 1979 and NAACP had been litigating the case since 1982. Attorneys asked and received reasonable attorney fees under Civil Rights Attorney’s Fees Awards Act of 1976‚ 42 U.S.C. §1988. All fees were given at current market rates. A Court of Appeals affirmed this
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violated the First Amendment. In trying to keep minors away from inappropriate material the Act reduced "the freedom of speech" by restricting what adults could send over the internet. # 2) Legal Precedent: a. Sable Communications of California v. FCC (1989) was in response to a ban on indecent and obscene interstate commercial phone messages. Sable Communications was in the dial-a-porn business. The supreme court decision was that the ban on obscene speech was valid since the constitution does
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Janel Mitchell Ms. Winter Honors Civics & Economics B-1 Case name: DC V. Heller A controversial topic came about in the year of 2008. It was concerning whether or not DC’s gun law was following along the lines of the Second Amendment Rights. A man by the name of Dick Anthony Heller was a special police officer and had gone in to register for a handgun for his home. The true underlying issue was whether or not the rights were protected under the Second Amendments which states: The
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