occurs when the coronary arteries that supply the heart blood become narrowed‚ and eventually occluded. This narrowing typically takes place because of plaque build up due to cholesterol and other fatty substances being ingested‚ also called atherosclerosis. This thickening of the artery wall can take many years‚ eventually completely inhibiting blood flow. Because the blood flow has stopped‚ little oxygen gets to the heart‚ and the myocardial cells therefore die. This is when a heart attack ensues
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death in the adult population in the United States. The primary cause of heart disease is coronary artery atherosclerosis‚ which is the build- up of plaque in the artery walls. This plaque is the result of the oxidation of LDL cholesterol. Over time‚ this plaque can significantly slow or even prevent the flow of blood to the heart. It is believed that the development of atherosclerosis is a result of an abundance of free radicals in our bodies. These free radicals are
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There are three main types of treatment for Coronary Heart Disease: lifestyle‚ medication‚ and‚ for advanced atherosclerosis‚ special procedures. The first two types of treatment also can help prevent the development of Coronary Heart Disease. The Lifestyle treatment has 6 main steps to help you prevent or control CHD. They are‚ stop smoking cigarettes‚ lower high
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heart disease (CHD) is a disease in which a waxy substance called plaque (plak) builds up inside the coronary arteries. These arteries supply oxygen-rich blood to your heart muscle. When plaque builds up in the arteries‚ the condition is called atherosclerosis (ATH-er-o-skler-O-sis). The buildup of plaque occurs over many years. (nhlbi.nih.gov) CHD AND TREATMENTS: CHD is the most common type of heart disease. In the United States‚ CHD is the #1 cause of death for both men and women. Lifestyle
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Cardiovascular disease is among the most common disease that cause early mortality. There have been an inexhaustible amount of studies on cardiovascular disease. It can be a preventable and controllable disease with the proper nutrition‚ exercise‚ and dedication. People for centuries have been dying early deaths because they did not know how to take care of their own body. Now that we have reached the 21st century‚ we have the medical knowledge as well as the tools to better prevent disease such
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leading to the heart becomes completely blocked and the heart does not get enough blood or oxygen‚ causing cells in that area of the heart to die (called an infarct). Most heart attacks are caused by blood clots‚ which are in turn caused by atherosclerosis (stiffening and narrowing of the arteries). High blood fats (triglycerides) and LDL or “bad” cholesterol form plaque inside arteries‚ narrowing the passageway and reducing the amount of blood that can flow through. A person’s lifestyle plays a
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body to be unable to remove and regulate the amounts of low density lipoprotein (LDL). [1] Due to its hereditary source‚ Familial Hypercholesterolemia usually begins at an early age‚ causes heart attacks and contributes to the development of Atherosclerosis. The human body regulates concentrations of low density lipoprotein in the body using LDL receptor genes‚ [2] but missense mutations can sometimes occur in the coding sequences of these receptors‚ which would result in the formulation of the disorder
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Lipids‚ which are also known as fats play a very important part in our bodies‚ it provides energy to producing hormones. As humans we wouldn’t be able to digest and absorb food without lipids. Eating more fat than we need can lead to weight gain but with proper amounts of lipids they are a healthy part of our diet. The main role of lipids in our body is to provide energy for muscles and body processes. Half of the fuel our body needs when at rest or with everyday activity comes from lipids. Lipids
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of cholesterol in the walls of your arteries and takes it to the liver to be removed from your body through the intestines. HDL is referred to as "good" cholesterol because of its protective effect against atherosclerosis. Higher HDL concentrations correlate with lower rates of atherosclerosis and a lower risk for heart disease and stroke. LDL is the primary cholesterol transporter in your bloodstream. Your body uses cholesterol to produce protective walls around your cells and steroid hormones.
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must present two successful studies with the intended outcome. Niaspan has the FDA indication to raise HDL-C‚ reduce secondary non-fatal myocardial infarction‚ and regression of atherosclerosis in combination with a bile acid resin. In a recent study (cite) patients taking Niaspan demonstrated regression of atherosclerosis in combination with statin‚ a popular cholesterol treatment agent. Abbott is now looking to replicate the study in order to receive an additional FDA indication and extended patent
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