constrict which eventually causes high blood pressure. Additionally‚ smoking seems to accelerate the process of hardening of the arteries‚ also known as "Atherosclerosis". Nicotine stays along the artery wall causing it to become thickened and less elastic. As these plaques or thickened secretions develop and hardened‚ the progress of Atherosclerosis causes even more serious problems in the cardiovascular system‚ such as heart attack and stroke. Plaques can also break‚ creating blood clots‚ which completely
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Atherosclerosis can affect the arteries of the heart and it’s called coronary artery disease. Coronary atherosclerosis is mainly characterized by build-up of plaques in artery wall ‚ which formed by lipids‚ cholesterol‚ macrophages ‚ and smooth muscle cells accumulation as intimate plaques in the large and medium-sized epicardial coronary arteries.(1‚2‚3) The development of atherosclerosis usually follows the endothelial dysfunction‚ which increase the permeability to and accumulation of oxidized
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Atherosclerosis is also known as an arteriosclerotic vascular disease‚ it is a condition were the arteries in the heart become hard‚ narrow and thick because of the buildup of cholesterol and plaque. Plaque is made of sticky material that is formed when cholesterol is combined with fat‚ calcium and fibrin (a clotting material in the blood) around the artery walls. Arteries have an endothelium‚ it is a thin layer which maintains the artery smooth and allows the blood to flow easily‚ Atherosclerosis
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Case Study 1: Atherosclerosis In order to survive the human body requires oxygen. Oxygen is obtained by inhalation or by drinking water. The oxygen obtained is absorbed by the blood stream in the lungs and the heart begins to circulate it to every organ‚ tissue‚ and cell in the body. The human heart pumps blood through veins‚ arteries‚ and capillaries all the time in order to stay alive. A heart attack occurs when cells in the heart cannot receive enough oxygen because not enough blood is being
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Atherosclerosis A number of ageing changes occur in the aorta‚ arteries and arterioles. The age related changes that occur in muscular arteries are usually known as arteriosclerosis. It involves alterations of the smooth muscle hypertrophy and intimal fibrosis further reducing the diameter of the vessel. Atherosclerosis is the most common arterial abnormality known as arteriosclerosis which is defined as the stiffening or hardening of the artery walls. However‚ atherosclerosis refers to the hardening
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Azam Khorshidi Dissecting the role of ANRIL in modulating endothelial cells function and atherosclerosis Name: Azam (Anna) Khorshidi Department: Laboratory Medicine & Pathobiology Program: PhD Supervisor: Dr. Burton Yang Topic of graduate study: Role of miR-17 in the breast cancer initiation and progression Key words: Atherosclerosis‚ Plaque formation‚ lncRNA‚ Endothelia dysfunction Email: anna.khorshidi@mail.utoronto.ca 1 Azam Khorshidi Impact: Endothelial dysfunction is
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lesion of atherosclerosis is the fatty streak‚ which is due to an accumulation of lipid-laden foam cells in the intimal layer of the artery. With time‚ the fatty streak evolves into a fibrous plaque‚ the hallmark of established atherosclerosis. Ultimately the lesion may evolve to contain large amounts of lipid; if it becomes unstable‚ denudation of overlying endothelium‚ or plaque rupture‚ may result in thrombotic occlusion of the overlying artery. http://www.nhs.uk/Conditions/Atherosclerosis/Pages/Causes
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Coronary Artery Disease Coronary artery disease Definition “Coronary artery disease is a type of blood vessel disorder that is included in the general category of atherosclerosis. Atherosclerosis is derived from two Greek words: athero‚ meaning “fatty mush” and skleros‚ meaning “hard.” Atherosclerosis is often referred to as “hardening of the arteries.” Although this condition can occur in any artery in the body‚ the atheromas (fatty deposits) have a preference for coronary arteries”(Lewis &
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Popliteal aneurysms are swelling of an artery. They are thought to be caused by atherosclerosis. These aneurysms are also correlated with the causes that develop aortic aneurysms. The wall of the popliteal artery is weakened‚ and thought to be because of inherited factors. In patients with multiple aneurysms in different arteries‚ it is theorized that there is an underlying weakness in the tissues. The exact nature of this has not been clarified at this time. Possibly the propensity of the
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Arterial Disease April 22‚ 2010 ME 1352 Abstract Peripheral Arterial Disease is a common secondary disease that follows Atherosclerosis. Once so much plaque builds up in the arteries‚ they become block the blood flow. P.A.D. usually affects the lower extremities and can cause intermittent claudication and‚ if severe enough‚ gangrene. Many people live with atherosclerosis and P.A.D. and show no symptoms. There are numerous prevention methods for P.A.D that is similar to preventing any cardiovascular
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