Introduction: The purpose of this lab was to learn how to use salicylic acid to make aspirin. Aspirin is the most widely used over-the-counter drug in the world. The average tablet contains about 325 milligrams of acetylsalicylic acid with an inert binding material such as starch. Aspirin is used to relieve pain‚ reduce inflammation‚ and lower fever. Aspirin originally was derived by boiling the bark of the white willow tree. Although the salicin in willow bark has analgesic properties‚ purified
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Lab Report Synthesis and Characterization of Aspirin (Acetylsalicylic Acid) The Synthesis and Characterization of Aspirin (Acetylsalicylic Acid). Summary: In this experiment‚ we produced 4.21 g of acetylsalicylic acid. Our theoretical yield was calculated to be 5.22 g. Therefore our % yield was determined to be 80.6%. The experimental boiling point range of acetylsalicylic acid was found to be 130-132° C. The true melting point of acetylsalicylic acid is 135° C‚ therefore our percent
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LIDE Learning Center‚ Inc. 6539 Isabel‚ Leyte Synthesis of Aspirin An Investigatory Project Presented to: Edmundo A. Quiñones Chemistry Teacher In Partial Fulfillment of the Requirements In Science and Technology III (Chemistry) Presented by: Kenneth Ivan P. Durano Cyrill Val G. Lozano March 6‚ 2010 APPROVAL SHEET This investigatory project entitled “The Synthesis of Aspirin” requirement for Science and Technology III (Chemistry) has
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x 10-3‚ as shown in Equation 3. The purified aspirin product was a white powder that had a weight of .140 g. The number of moles of the purified aspirin product after extraction was 7.77 x 10-4 as shown in Equation 4. These two moles calculated a chemical yield of 54.3% as shown in Equation 5. The melting point of the pure aspirin product was ranged at 117.8-125.2C as shown in Table 1. An infrared spectrum for the pure aspirin from the synthesis was taken by using crushed crystals‚ Figure 1
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Synthesis of Aspirin and Tylenol Kyla Wykoff Abstract Aspirin and Tylenol were synthesized by means of crystallization‚ recrystallization‚ and melting point determination. Synthesis produced significantly high percent yields for aspirin‚ however‚ produced extremely low and impure percent yields for Tylenol. A second group was also used to compare results and errors‚ in which they too were also producing extremely low percent yields of Tylenol. Therefore‚ error was based on the specific protocol
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crystals 95% ethanol Clear colorless liquid Acetyl chloride Clear colorless liquid with gas escaping from container FeCl3 Clear colorless liquid Commercial aspirin Fine powdery white solid crystals I2/KI Deep black liquid KMnO4 Brownish liquid Phosphoric acid Clear colorless liquid Table 2. Preparation of Aspirin. Description Salicylic acid + Acetyl chloride Cloudy white liquid with undissolved white powder Mixture at room temp White cloudy liquid Mixture in ice bath
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SYNTHESIS OF THE PHARMACEUTICAL ASPIRIN (ACETYLSALICYLIC ACID) AIM: The aim for this experiment was to synthesise a small amount of aspirin with salicylic acid as the starting product and sulphuric acid as the catalyst. The product obtained from this reaction will be impure and will need to be purified. This will be done by recrystallization. We will then record the products’ melting point and calculate the yield in order to determine the degree of purity of the aspirin sample. Diagrammatic scheme
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to synthesise acetylsalicylic acid (aspirin) by creating a reaction between acetic anhydride and salicylic acid. This was be accomplished through the use of recrystallization. Acetic anhydride and salicylic acid are mixed together‚ and then acidified by the addition of a few drops of concentrated sulfuric acid‚ which catalyzed the reaction. The percent yield is calculated to determine the effectiveness of the reaction in preparing the desired product (aspirin). The limiting reactant of the equation
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Safety Precautions for Synthesis of Acetic Anhydride Acetic Anhydride Acetic anhydride is an irritant and also flammable‚ therefore gloves and goggles should be worn at all times during the experiment. It is reactive to water‚ so in the case of fire‚ alcohol foam or carbon dioxide is preferred to use as an extinguisher. This chemical has harmful fumes and use of a fume hood is strongly recommended. Sulphuric and Salicylic Acid These acids may irritate the skin in high concentrations. Take
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Synthesis of Aspirin (Acetylsalicylic Acid) Abstract: This experiment is about the synthesis of aspirin under laboratory conditions. Aspirin is prepared by reacting salicylic acid and acetic anhydride; in the presence of sulfuric acid. After fully dissolving the salicylic acid with acetic anhydride‚ the solution is cooled and cold water is then added. Once the crystals form they are then filtered and left to dry out. There mass is measured and recorded then the yield is calculated. Introduction:
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