BMS3021 – Research Topic: Aspirin TOPIC SUMMARY Aspirin is able to inhibit the synthesis of the Thromboxane A2 precursor‚ by irreversibly binding to the COX-1 enzyme Lack of Thromboxane A2 means that there is no signalling for platelet aggregation so there is no blood clot formation‚ leading to its ability to act as a ‘blood thinner‘ SALT found that in a low-dose of 75mg of Aspirin a day‚ secondary prophylaxis of new cardiovascular events were reduced by 16-20% By decreasing the daily dose to 75mg
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1cm/7.4cm = .689 Rf1 Unknown 5.0cm/7.4cm = .676 Rf2 Aspirin 5.0cm/7.4cm = .676 Rf3 Acetaminophen 2.9cm/7.4cm = .392 Rf4 Ibuprofen 2.9cm/7.4cm = .392 Rf5 Salicylamide 5.0cm/7.4cm = .676 Rf6 Caffeine 1.0cm/7.4cm = .135 Trial 2: Rf1 Unknown 5.0cm/7.4cm = .676 Rf1 Unknown 5.0cm/7.4cm = .676 Rf2 Aspirin 5.2cm/7.4cm = .703 Rf3 Acetaminophen 3.3cm/7
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sakshieducation.com www.sakshieducation.com b) Non - narcotic analgesics: These drugs are analgesics but they have no addictive properties. Their analgesic use is limited to mild aches and pains like backache and headache. Ex: Aspirin‚ Ibuprofen etc. Aspirin: Chemically aspirin is ortho acetyl salicylic acid. Preparation: Acetylation of salicylic acid with acetic
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Bristol-Myers have been very successful in analgesic market for many years with Aspirin type pain relievers marketed as Bufferin and Excedrin. Together with Bayer Aspirin by Sterling Drug Company‚ three aforementioned aspirin type pain relievers comprised of 90% of Analgesic market. One other type of pain relievers‚ Acetaminophen‚ have emerged into the market and its growth in the market seemed quite significant compared to that of aspirin type pain relievers. Although acetaminophen comprised of less than 10%
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gov/Food/DietarySupplements/Alerts/ucm111208.htm FDA Safety Update: Asthma Medications. (2008). Retrieved from http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm048223.htm Possible Side Effects (2012). Retrieved from Aspirin for Reducing Your Risk of Heart Attack and Stroke: Know the Facts. (2012). Retrieved from Aspirin- PubMed Health. (2011). Retrieved from http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000802/ National Reye ’s Syndrome Foundation . (2011). Retrieved from http:// http://www.reyessyndrome.org/ Salicylate
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product‚ are done on a much larger scale in industry. The aspects they may differ in are equipment‚ time taken‚ and many other things. In this report I will explain how and why laboratory and industrial scale differ using the example of preparation of aspirin. The first difference is that instead of weighing the 2-hydroxybenzoic acid on scales on a work bench in a beaker as you would in small scale‚ it is easier and safer to weigh it onto scales‚ in a plastic bag on the floor. This is easier and safer
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First aid Introduction First aid is the provision of initial care for an illness or injury. It is usually performed by non-expert‚ but trained personnel to a sick or injured person until definitive medical treatment can be accessed. Certain self-limiting illnesses or minor injuries may not require further medical care past the first aid intervention. It generally consists of a series of simple and in some cases‚ potentially life-saving techniques that an individual can be trained to perform with
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Synthesis of Aspirin from Oil of Wintergreen Objectives: In this experiment‚ the Oil of Wintergreen is put into an Erlenmeyer flask containing sodium hydroxide to create sodium salicylate. The solution is then refluxed which means that the solution will be boiled in a base‚ then condensed in a condenser. This replaces the carbon on the ester at carbon 1‚ with an oxygen atom which will have an ionic bond with a sodium anion. This yields sodium salicylate which will be acidified in methanol
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to be triggered by aspirin use. The actual origin of the disease is unknown. Reye’s Syndrome‚ occasionally called Reye-Jacobsen’s Syndrome‚ is known to follow any viral infection. Two of the most common viral infections it precedes is influenza‚ "the flu"‚ and chicken pox. A now-familiar warning on bottles of aspirin‚ most notably Tylenol‚ is not to give Tylenol to a child who is recovering from the chicken pox‚ a fever‚ or any other viral infection. The link between aspirin and Reye’s Syndrome
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chloride‚ creating acetylsalicylic acid. Where the Molecule can be Found This molecule also known as aspirin can be found everywhere in our surroundings. People in our community today including myself very commonly use it. In can be found in household cabinets‚ behind the counter medicines‚ in medicines themselves‚ and in nature. How the Molecule is Created Aspirin tablets of the same dosage amount are manufactured in batches. After careful weighing‚ the necessary ingredients
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