Susan Chong DSR 610 6 May 2015 EZH2 and Notch1 signaling in glioblastomas and breast cancer stem cells Within a tumor exists a subpopulation of cells that present less abnormal characteristics; however‚ there exists another type that hold the potential to recreate and expand tumor mass. The latter share similar characteristics to normal stem cells‚ which are the unlimited ability to self-renew and the ability to maintain undifferentiated. Over the course of time‚ these cells will differentiate into
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Cancer Institute at Cedars-Sinai Medical Center‚ pepper component caused human prostate cancer cells to unde4rgo programmed cell death or apoptosis. When an experiment was preformed amongst a few mice‚ the result where evident. Caspsaicin induced approximately 80 percent of prostate cancer cells growing in mice to follow the molecule pathways leading to apoptosis. Prostate cancer tumors treated with caspsaicin were about one-fifth the size of tumors in non-related mice.
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Chapter 33 notes: Intrinsic cellular defense against virus infection 1. Toll- like receptors sense virus infections a. Toll-like receptors (TRL) i. Located on the cell surface or in endosomal membranes = recognize conserved structures found in pathogens ii. Highly conserved receptors from flies humans iii. Most mammals have between 10-15 (humans = 10) iv. TLR – 2: lipoproteins/glycoproteins (mealsels‚ hepB‚ herpes) v. TLR– 3: dsRNA (west
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Bibliography: • Fauci‚ A. et. al. (2005) Harrison ’s Principle of Internal Medicine‚ 17th edition. New York: McGraw-Hill Companies‚ Inc. • Hughes‚ David ‚ and Huseyin Mehmet. (2003) Cell Proliferation and Apoptosis. New York: Garland Science. • Medina‚ L.V. et al. (2010) Philippine Cancer Facts and Estimates. Manila: Philippine Cancer Society. • Pizzorno‚ J. E.‚ & Murray‚ M. (2005).Textbook of Natural Medicine e-dition: Text with Continually Updated Online
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Johnson Syndrome is an inmune disease charactherized by a detachment of the epidermis from dermis. It could be fatal and the pathophysilogy involves a complex hypersensitivity reaction with the participation of T lymphocytes that induce keratinocyte’s apoptosis. The syndrome can be cause by drigs‚ infections and malignancies. The diagnosis is difficlut due to the abscense of specific manifestations and laboratory tests. There is a genetic predisposition in individuals with certain HLA types. The disease
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1. Rosalind Franklin’s discovered that DNA contains nitrogenous bases the principle of base pairing the X-ray diffraction pattern of DNA‚ which helped uncover its double helix structure how to sequence DNA molecules the bonding energy of DNA molecules 2. Which of the following carries amino acids to ribosomes‚ where amino acids are linked into the primary structure of a polypeptide? mRNA tRNA hnRNA rRNA all of these 3. The nitrogenous base
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Mechanisms of Acetaminophen-lnduced Liver Necrosis By Jack A. Hinson‚ Dean W. Roberts‚ and Laura P. James Acetaminophen (paracetamol‚ N-acetyl-p-aminophenol; APAP) is widely used as analgesic and antipyretic drug. At therapeutic doses‚ acetaminophen is safe to be used. Acetaminophen other than aspirin and ibuprofen has only weak anti-inflammatory properties. At higher doses‚ acetaminophen produces a centrilobular hepatic necrosis that can be fatal. Acetaminophen-lnduced Hepatotoxicity Observation/
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factors send molecular signals that tell cells to divide. 4. Cells divide‚ differentiate‚ or die. What is differentiation? Differentiation is when a cell stops dividing to perform a special function or to change shape. 5. What is apoptosis? Explain its purpose. Apoptosis is a process that eliminates unnecessary cells during development and destroys damage or unhealthy cell in a mature organism. 6. Organisms maintain the right number of cells by regulating the cell cycle. What are “cell cycle regulators”
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HeLa Cells are Important to Science Henrietta Lacks‚ a poor black woman in the 1950’s‚ unknowingly had samples taken from her cervical cancer specimen and changed science from that point on. Due to the continuous self-reproduction of the cells‚ HeLa cells are the most important cell line ever discovered by scientists to date! Popsci.com gave five reasons of why HeLa cells are so important to society. Popsci.com explained‚ “1. Before HeLa cells‚ scientists spent more time trying to keep cells alive
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activation of plasmin. Macrophages can also endocytose IgG-bound latent TGF-beta complexes that are secreted by plasma cells and then release active TGF-beta into the extracellular fluid.[2] Contents 1 The Structure of TGF-β 2 Function 2.1 Apoptosis 2.1.1 SMAD pathway 2.1.2 DAXX pathway 2.2
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